C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: microtubule-actin crosslinking factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028649 Macf1 10090 - 4:123349633-123684360 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000082108 Macf1-001 123349716-123684360 protein_coding
  ENSMUST00000084301 Macf1-201 123349718-123684360 protein_coding
  ENSMUST00000097897 Macf1-202 123349633-123684360 protein_coding
  ENSMUST00000106213 Macf1-004 123349716-123476367 protein_coding
  ENSMUST00000106220 Macf1-203 123349718-123527459 protein_coding
  ENSMUST00000106224 Macf1-013 123349720-123684360 protein_coding
  ENSMUST00000123765 Macf1-003 123349633-123369931 protein_coding
  ENSMUST00000125447 Macf1-012 123397275-123407515 processed_transcript
  ENSMUST00000134458 Macf1-008 123349716-123499917 protein_coding
  ENSMUST00000140596 Macf1-011 123383129-123390538 protein_coding
  ENSMUST00000146000 Macf1-006 123538880-123564694 processed_transcript
  ENSMUST00000147030 Macf1-005 123456349-123664752 protein_coding
  ENSMUST00000147228 Macf1-007 123456349-123527648 protein_coding
  ENSMUST00000149022 Macf1-010 123349716-123366449 protein_coding
  ENSMUST00000151346 Macf1-009 123349716-123544831 protein_coding
  ENSMUST00000154824 Macf1-002 123349716-123372367 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000082108ENSMUST00000106213ENSMUST00000123765ENSMUST00000134458ENSMUST00000149022ENSMUST00000151346ENSMUST00000154824
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000082108 N/A N/A N/A 5.182±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000106213 2.305±0.00 N/A 1.826±0.00 N/A 1.669±0.02 1.230±0.27 1.987±0.44 1.171±0.00 0.359±0.04 9.087±0.59 0.597±0.11 N/A N/A N/A
ENSMUST00000123765 N/A N/A 13.578±0.00 N/A N/A N/A N/A N/A 1.981±0.00 N/A N/A N/A 9.348±0.00 N/A
ENSMUST00000134458 N/A 1.860±0.41 N/A 8.727±3.75 4.394±0.00 1.743±0.38 N/A 1.446±0.00 0.909±0.00 N/A 0.774±0.11 4.535±1.82 6.930±2.82 N/A
ENSMUST00000149022 N/A 6.902±0.70 18.682±0.00 N/A N/A 18.369±2.85 N/A 13.627±3.34 4.275±1.35 N/A N/A 11.766±1.16 N/A N/A
ENSMUST00000151346 N/A N/A N/A 5.172±0.00 3.968±1.21 1.358±0.10 2.117±0.61 2.205±0.00 0.793±0.28 8.869±0.50 0.731±0.12 7.429±3.73 7.474±6.24 2.375±1.25
ENSMUST00000154824 23.469±4.62 20.330±5.55 14.143±2.32 46.138±11.95 35.400±15.86 14.483±2.25 16.244±2.65 11.862±1.35 5.035±2.02 95.476±12.62 4.739±1.05 29.351±8.94 10.866±1.11 5.784±0.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000990 CIL_000990_0002 VISTA 4:123304867-123907516
CIL_0001ZU CIL_0001ZU_0002 CGP 4:123349633-123718202

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001707 IMP mesoderm formation
GO:0003779 IDA actin binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005794 IEA Golgi apparatus
GO:0005874 IEA microtubule
GO:0005886 IEA plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006620 IMP posttranslational protein targeting to membrane
GO:0006928 IMP cellular component movement
GO:0007050 IEA cell cycle arrest
GO:0007163 IMP establishment or maintenance of cell polarity
GO:0008017 IDA microtubule binding
GO:0015629 IDA actin cytoskeleton
GO:0015630 IDA microtubule cytoskeleton
GO:0016055 IGI Wnt signaling pathway
GO:0016887 IEA ATPase activity
GO:0032587 IEA ruffle membrane
GO:0032886 IEA regulation of microtubule-based process
GO:0043001 IEA Golgi to plasma membrane protein transport
GO:0044822 IEA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028533 macf1 microtubule-actin crosslinking factor 1 protein_coding Danio_rerio
ENSG00000127603 MACF1 microtubule-actin crosslinking factor 1 protein_coding Homo_sapiens

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