C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: amyloid beta (A4) precursor protein-binding, family B, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029207 Apbb2 10090 - 5:66298861-66618828 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000087256 Apbb2-201 66301888-66618671 protein_coding
  ENSMUST00000159357 Apbb2-015 66452261-66514837 protein_coding
  ENSMUST00000159512 Apbb2-003 66301888-66618782 protein_coding
  ENSMUST00000159786 Apbb2-001 66298861-66618828 protein_coding
  ENSMUST00000159847 Apbb2-010 66540702-66618688 retained_intron
  ENSMUST00000160054 Apbb2-020 66312231-66313439 retained_intron
  ENSMUST00000160063 Apbb2-017 66364974-66451629 protein_coding
  ENSMUST00000160103 Apbb2-011 66452024-66618671 protein_coding
  ENSMUST00000160185 Apbb2-006 66399622-66618682 retained_intron
  ENSMUST00000160775 Apbb2-018 66301872-66337663 processed_transcript
  ENSMUST00000160870 Apbb2-007 66301872-66618663 protein_coding
  ENSMUST00000161716 Apbb2-012 66452267-66546957 protein_coding
  ENSMUST00000161771 Apbb2-019 66307583-66337483 processed_transcript
  ENSMUST00000161879 Apbb2-016 66451995-66514830 protein_coding
  ENSMUST00000161936 Apbb2-013 66461914-66618672 processed_transcript
  ENSMUST00000162349 Apbb2-004 66301888-66618681 protein_coding
  ENSMUST00000162366 Apbb2-008 66301888-66618758 protein_coding
  ENSMUST00000162382 Apbb2-014 66451982-66618640 protein_coding
  ENSMUST00000162401 Apbb2-005 66399616-66618669 retained_intron
  ENSMUST00000162955 Apbb2-002 66301888-66337665 processed_transcript
  ENSMUST00000162994 Apbb2-009 66452228-66618774 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000159512ENSMUST00000159786ENSMUST00000159847ENSMUST00000160063ENSMUST00000160775ENSMUST00000160870ENSMUST00000161879ENSMUST00000162349ENSMUST00000162366ENSMUST00000162955ENSMUST00000162994
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000159512 N/A 2.448±0.78 N/A N/A 1.004±0.14 1.043±0.27 N/A 2.027±0.00 0.354±0.00 1.768±0.04 N/A 3.262±1.16 N/A N/A
ENSMUST00000159786 2.958±1.45 2.867±0.49 1.925±0.28 3.576±2.27 1.788±0.67 0.574±0.18 1.554±0.22 2.433±0.69 0.244±0.12 5.461±1.62 N/A 2.921±1.17 2.884±1.38 N/A
ENSMUST00000159847 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.072±0.00
ENSMUST00000160063 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.606±0.00
ENSMUST00000160775 N/A N/A N/A 4.763±0.00 N/A N/A N/A N/A N/A N/A 4.124±0.87 N/A 5.724±0.00 N/A
ENSMUST00000160870 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.837±0.58 5.002±0.00 0.184±0.06
ENSMUST00000161879 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.412±0.00
ENSMUST00000162349 N/A N/A N/A N/A N/A 0.922±0.00 2.011±0.43 N/A 0.276±0.15 N/A N/A N/A 3.166±0.00 0.257±0.00
ENSMUST00000162366 N/A 2.169±0.50 N/A N/A 1.523±0.24 N/A N/A 1.781±0.11 0.737±0.28 1.857±0.08 N/A 2.548±1.30 N/A N/A
ENSMUST00000162955 N/A N/A N/A N/A 2.834±0.00 N/A N/A N/A N/A N/A 5.832±0.93 N/A N/A N/A
ENSMUST00000162994 N/A 7.366±1.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00038T CIL_00038T_0002 CGP 5:66259912-66618828
CIL_00038S CIL_00038S_0002 CGP 5:66298861-66687231

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IGI neuron migration
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007050 IDA cell cycle arrest
GO:0007411 IGI axon guidance
GO:0008134 IDA transcription factor binding
GO:0030048 NAS actin filament-based movement
GO:0030198 IGI extracellular matrix organization
GO:0030308 IDA negative regulation of cell growth
GO:0035035 NAS histone acetyltransferase binding
GO:0043065 IDA positive regulation of apoptotic process
GO:0043066 IGI negative regulation of apoptotic process
GO:0050821 NAS protein stabilization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026651 amyloid beta (A4) precursor protein-binding, family B, member 2 protein_coding Danio_rerio
ENSDARG00000061880 apbb2b amyloid beta (A4) precursor protein-binding, family B, member 2b protein_coding Danio_rerio
ENSG00000163697 APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 protein_coding Homo_sapiens

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