C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RasGEF domain family, member 1B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029333 Rasgef1b 10090 - 5:99217426-99252927 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031276 Rasgef1b-001 99217426-99252927 protein_coding
  ENSMUST00000166484 Rasgef1b-003 99218774-99243240 protein_coding
  ENSMUST00000166632 Rasgef1b-004 99227794-99234066 retained_intron
  ENSMUST00000168092 Rasgef1b-002 99217426-99252927 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031276ENSMUST00000166484ENSMUST00000166632ENSMUST00000168092
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031276 0.808±0.66 1.116±0.39 0.955±0.24 6.690±0.66 1.071±0.15 7.930±2.47 0.338±0.14 1.862±0.64 1.581±0.73 4.335±0.53 0.122±0.18 3.817±1.83 4.006±1.39 1.173±0.23
ENSMUST00000166484 N/A 1.810±0.00 N/A 9.584±0.00 N/A 8.169±1.47 N/A N/A N/A N/A 0.057±0.05 6.703±0.00 5.848±2.47 2.320±0.00
ENSMUST00000166632 N/A N/A N/A 32.723±0.00 N/A N/A N/A N/A N/A N/A N/A 14.643±0.00 19.807±4.80 1.556±0.00
ENSMUST00000168092 1.137±0.98 1.430±0.00 1.790±0.47 8.800±0.88 1.106±0.40 4.877±1.63 1.315±0.17 2.649±1.01 1.920±1.39 6.391±1.54 0.041±0.01 3.166±1.80 3.639±1.07 0.552±0.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000086 CIL_000086_0003 CGP 5:98929773-99252927
CIL_0008G8 CIL_0008G8_0002 VISTA 5:99067893-99670406

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005088 ISS Ras guanyl-nucleotide exchange factor activity
GO:0005768 IEA endosome
GO:0007264 IEA small GTPase mediated signal transduction
GO:0032320 ISS positive regulation of Ras GTPase activity
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033614 rasgef1ba RasGEF domain family, member 1Ba protein_coding Danio_rerio
ENSDARG00000044251 rasgef1bb RasGEF domain family, member 1Bb protein_coding Danio_rerio
ENSG00000138670 RASGEF1B RasGEF domain family, member 1B protein_coding Homo_sapiens

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