C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RasGEF domain family, member 1B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138670 RASGEF1B 9606 - 4:81426393-82044244 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264400 RASGEF1B-001 81427065-81471915 protein_coding
  ENST00000335927 RASGEF1B-005 81427449-81471904 protein_coding
  ENST00000436139 RASGEF1B-003 81450893-81471890 protein_coding
  ENST00000504863 RASGEF1B-006 81434676-81471907 protein_coding
  ENST00000507538 RASGEF1B-004 81458983-81471928 retained_intron
  ENST00000509081 RASGEF1B-002 81426393-81471236 protein_coding
  ENST00000512716 RASGEF1B-008 81459479-82044244 protein_coding
  ENST00000514889 RASGEF1B-007 81452029-81457602 processed_transcript
  ENST00000613784 RASGEF1B-201 81450894-81471890 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264400ENST00000335927ENST00000436139ENST00000504863ENST00000509081ENST00000613784
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264400 1.580±0.00 0.899±0.00 0.711±0.00 1.671±0.08 1.543±0.95 0.536±0.00 0.552±0.00 1.496±0.06 1.634±1.22 4.531±0.66 0.583±0.00 1.161±0.55 0.857±0.20 0.955±0.59
ENST00000335927 N/A N/A N/A N/A N/A N/A 0.165±0.00 3.930±0.00 0.775±0.00 3.525±0.46 N/A 0.647±0.03 2.681±0.00 N/A
ENST00000436139 N/A 0.276±0.00 0.750±0.00 N/A N/A 0.704±0.00 0.107±0.00 N/A N/A 1.426±1.05 N/A 0.754±0.00 N/A N/A
ENST00000504863 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.412±0.00 N/A N/A N/A
ENST00000509081 0.640±0.00 N/A N/A N/A 1.599±0.00 1.412±0.00 N/A N/A 0.402±0.00 N/A 1.089±0.00 N/A N/A 0.392±0.00
ENST00000613784 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.258±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000086 CIL_000086_0002 CGP 4:81087370-82044244
CIL_0008G8 CIL_0008G8_0001 VISTA 4:81293869-81895630

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005088 IDA Ras guanyl-nucleotide exchange factor activity
GO:0005622 IEA intracellular
GO:0005768 IEA endosome
GO:0007264 IEA small GTPase mediated signal transduction
GO:0032320 IDA positive regulation of Ras GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0051056 IEA regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033614 rasgef1ba RasGEF domain family, member 1Ba protein_coding Danio_rerio
ENSDARG00000044251 rasgef1bb RasGEF domain family, member 1Bb protein_coding Danio_rerio
ENSMUSG00000029333 Rasgef1b RasGEF domain family, member 1B protein_coding Mus_musculus

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