C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: paired box 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029706 Pax4 10090 - 6:28442334-28449353 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031718 Pax4-001 28442334-28449353 protein_coding
  ENSMUST00000164519 Pax4-002 28442334-28449251 protein_coding
  ENSMUST00000171089 Pax4-003 28442339-28449251 protein_coding
  ENSMUST00000174036 Pax4-004 28444673-28447180 retained_intron
  ENSMUST00000174194 Pax4-006 28442375-28447180 protein_coding
  ENSMUST00000174423 Pax4-005 28443804-28446864 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonLiverTestisENSMUST00000031718ENSMUST00000164519ENSMUST00000171089ENSMUST00000174036ENSMUST00000174194ENSMUST00000174423
Transcript ID Brain Colon Liver Testis
ENSMUST00000031718 N/A 0.270±0.14 0.007±0.00 0.131±0.00
ENSMUST00000164519 0.034±0.02 0.449±0.00 N/A N/A
ENSMUST00000171089 0.012±0.00 0.241±0.13 N/A N/A
ENSMUST00000174036 N/A N/A 0.016±0.00 N/A
ENSMUST00000174194 0.031±0.01 0.154±0.00 0.038±0.02 0.069±0.00
ENSMUST00000174423 0.009±0.00 0.259±0.00 N/A 0.027±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008LN CIL_0008LN_0002 VISTA 6:28095025-28698247
CIL_0001OH CIL_0001OH_0002 CGP 6:28427789-28449353
CIL_0001OG CIL_0001OG_0002 CGP 6:28442334-28935162

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001206 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IDA DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 TAS transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0007623 IEA circadian rhythm
GO:0009887 TAS organ morphogenesis
GO:0030154 IEA cell differentiation
GO:0031018 TAS endocrine pancreas development
GO:0042493 IEA response to drug
GO:0043066 IEA negative regulation of apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0045595 IMP regulation of cell differentiation
GO:0045597 IMP positive regulation of cell differentiation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0051591 IEA response to cAMP
GO:0060041 IEA retina development in camera-type eye

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021336 pax4 paired box 4 protein_coding Danio_rerio
ENSG00000106331 PAX4 paired box 4 protein_coding Homo_sapiens

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