C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: caspase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000031895 Casp2-001 ENSMUSG00000029863 10090 + 6:42264985-42282508 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031895
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031895 12.234±4.98 7.537±1.01 10.480±0.34 17.441±12.40 12.353±3.24 17.869±2.85 2.459±0.33 5.215±1.42 9.387±8.96 16.613±0.70 0.787±0.38 19.478±8.06 5.776±3.56 1.897±0.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006VH CIL_0006VH_0002 CGP 6:42261970-42282508
CIL_0006VM CIL_0006VM_0002 CGP 6:42264985-42315756

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001554 IEA luteolysis
GO:0003407 IEA neural retina development
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0006508 RCA proteolysis
GO:0006977 IEA DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007420 IEA brain development
GO:0007568 IEA aging
GO:0008233 RCA peptidase activity
GO:0008630 IBA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016020 IEA membrane
GO:0016485 IEA protein processing
GO:0019904 IEA protein domain specific binding
GO:0035234 IGI ectopic germ cell programmed cell death
GO:0043065 ISA positive regulation of apoptotic process
GO:0043066 ISA negative regulation of apoptotic process
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0071260 IEA cellular response to mechanical stimulus
GO:0097153 IDA cysteine-type endopeptidase activity involved in apoptotic process
GO:0097190 IDA apoptotic signaling pathway
GO:0097192 IMP extrinsic apoptotic signaling pathway in absence of ligand
GO:2001235 IGI positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000310447 CASP2-001 protein_coding Homo_sapiens 0 1568
ENST00000350623 CASP2-003 nonsense_mediated_decay Homo_sapiens 0 990
ENST00000392925 CASP2-005 protein_coding Homo_sapiens 0 512
ENST00000472067 CASP2-004 retained_intron Homo_sapiens 0 508
ENST00000481483 CASP2-006 retained_intron Homo_sapiens 0 422
ENST00000493642 CASP2-002 processed_transcript Homo_sapiens 0 1014
ENST00000619992 CASP2-201 protein_coding Homo_sapiens 0 1022

Loading