C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, Ca++ transporting, plasma membrane 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030302 Atp2b2 10090 - 6:113745669-114042613 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000089003 Atp2b2-004 113745669-113891539 protein_coding
  ENSMUST00000101044 Atp2b2-003 113748294-113934681 protein_coding
  ENSMUST00000101045 Atp2b2-001 113745675-114042026 protein_coding
  ENSMUST00000135199 Atp2b2-005 113803338-113891370 retained_intron
  ENSMUST00000144507 Atp2b2-006 113842331-113910582 processed_transcript
  ENSMUST00000152831 Atp2b2-002 113745670-114042015 nonsense_mediated_decay
  ENSMUST00000154738 Atp2b2-007 113842549-114042613 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000089003ENSMUST00000101044ENSMUST00000101045ENSMUST00000135199ENSMUST00000144507ENSMUST00000152831ENSMUST00000154738
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000089003 0.643±0.11 0.705±0.17 N/A 12.306±10.16 0.034±0.00 0.128±0.01 0.108±0.00 0.123±0.03 0.384±0.20 N/A 0.033±0.00 N/A 0.044±0.05 N/A
ENSMUST00000101044 0.581±0.54 0.304±0.17 0.035±0.00 N/A 0.046±0.04 0.074±0.03 0.083±0.01 N/A 0.183±0.09 0.826±0.33 0.045±0.00 3.248±0.40 0.034±0.03 0.126±0.00
ENSMUST00000101045 0.885±0.85 0.109±0.00 0.060±0.00 14.558±0.00 0.062±0.00 0.090±0.00 0.101±0.06 0.329±0.07 N/A 0.172±0.03 0.017±0.01 1.234±0.61 N/A N/A
ENSMUST00000135199 N/A N/A N/A N/A N/A 0.105±0.02 N/A N/A 0.139±0.00 N/A 0.026±0.01 N/A N/A N/A
ENSMUST00000144507 N/A N/A N/A N/A 0.222±0.01 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000152831 0.085±0.00 N/A N/A 1.516±0.00 N/A 0.162±0.05 0.115±0.02 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000154738 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.096±0.02 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00064R CIL_00064R_0002 CGP 6:113728067-114042613
CIL_0001NW CIL_0001NW_0002 CGP 6:113745669-114249886

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IMP cell morphogenesis
GO:0005388 ISS calcium-transporting ATPase activity
GO:0005509 ISS calcium ion binding
GO:0005515 IEA protein binding
GO:0005516 ISS calmodulin binding
GO:0005524 ISS ATP binding
GO:0005737 ISS cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005886 ISS plasma membrane
GO:0005929 IDA cilium
GO:0006200 IMP ATP catabolic process
GO:0006816 IMP calcium ion transport
GO:0006874 IMP cellular calcium ion homeostasis
GO:0006996 IMP organelle organization
GO:0007595 IMP lactation
GO:0007605 ISS sensory perception of sound
GO:0007626 IMP locomotory behavior
GO:0008022 ISS protein C-terminus binding
GO:0008361 IMP regulation of cell size
GO:0016021 IEA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0021549 IMP cerebellum development
GO:0021692 IMP cerebellar Purkinje cell layer morphogenesis
GO:0021702 IMP cerebellar Purkinje cell differentiation
GO:0021707 IMP cerebellar granule cell differentiation
GO:0030165 ISS PDZ domain binding
GO:0030182 ISS neuron differentiation
GO:0030899 IMP calcium-dependent ATPase activity
GO:0040011 IMP locomotion
GO:0042428 IMP serotonin metabolic process
GO:0042472 IMP inner ear morphogenesis
GO:0043025 IDA neuronal cell body
GO:0045299 IMP otolith mineralization
GO:0046068 IMP cGMP metabolic process
GO:0046872 IEA metal ion binding
GO:0048167 IMP regulation of synaptic plasticity
GO:0048839 IMP inner ear development
GO:0050808 IMP synapse organization
GO:0050885 IMP neuromuscular process controlling balance
GO:0050910 IMP detection of mechanical stimulus involved in sensory perception of sound
GO:0051480 IMP cytosolic calcium ion homeostasis
GO:0051928 IMP positive regulation of calcium ion transport
GO:0060088 IMP auditory receptor cell stereocilium organization
GO:0060113 IMP inner ear receptor cell differentiation
GO:0070588 IEA calcium ion transmembrane transport
GO:0090102 IMP cochlea development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063433 atp2b2 ATPase, Ca++ transporting, plasma membrane 2 protein_coding Danio_rerio
ENSG00000157087 ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 protein_coding Homo_sapiens

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