C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytoplasmic FMR1 interacting protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030447 Cyfip1 10090 + 7:55841745-55930700 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032629 Cyfip1-001 55842071-55930700 protein_coding
  ENSMUST00000085255 Cyfip1-002 55842206-55930498 protein_coding
  ENSMUST00000163845 Cyfip1-006 55842255-55930471 protein_coding
  ENSMUST00000168271 Cyfip1-003 55841745-55892431 protein_coding
  ENSMUST00000173267 Cyfip1-004 55897074-55930498 retained_intron
  ENSMUST00000173384 Cyfip1-007 55897819-55904255 retained_intron
  ENSMUST00000173497 Cyfip1-005 55842250-55925786 retained_intron
  ENSMUST00000173783 Cyfip1-008 55842072-55878003 protein_coding
  ENSMUST00000174660 Cyfip1-009 55896745-55900840 retained_intron
  ENSMUST00000174793 Cyfip1-010 55908372-55913712 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032629ENSMUST00000085255ENSMUST00000163845ENSMUST00000173267ENSMUST00000173497ENSMUST00000174660
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032629 10.636±5.60 7.000±2.90 8.382±0.35 2.980±0.10 6.627±3.05 N/A 2.401±1.16 5.101±1.57 3.114±1.35 13.592±2.14 3.300±0.62 13.441±5.31 6.249±3.35 0.805±0.35
ENSMUST00000085255 5.152±0.67 12.161±5.34 3.652±0.00 9.011±1.64 7.192±0.51 13.532±3.24 2.833±0.12 6.004±1.07 2.573±1.94 5.157±1.07 0.828±0.06 11.024±3.31 5.535±2.80 1.584±0.28
ENSMUST00000163845 6.066±2.46 N/A 7.018±1.08 N/A 10.732±7.30 4.798±0.00 2.895±0.47 N/A 2.765±1.58 6.778±0.19 1.536±0.28 10.003±3.44 9.922±4.92 0.811±0.27
ENSMUST00000173267 N/A N/A N/A 2.087±0.26 N/A 5.112±0.96 N/A N/A N/A N/A N/A N/A N/A 0.423±0.07
ENSMUST00000173497 N/A 4.850±1.35 N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.889±0.14 N/A N/A
ENSMUST00000174660 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.652±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006L9 CIL_0006L9_0002 CGP 7:55794148-55930700
CIL_0003A6 CIL_0003A6_0002 CGP 7:55841745-55962476

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 ISS ruffle
GO:0005515 IPI protein binding
GO:0005522 TAS profilin binding
GO:0005845 IDA mRNA cap binding complex
GO:0005925 IEA focal adhesion
GO:0008360 IEA regulation of cell shape
GO:0016601 IEA Rac protein signal transduction
GO:0030027 IDA lamellipodium
GO:0030032 IDA lamellipodium assembly
GO:0030054 IEA cell junction
GO:0031209 IEA SCAR complex
GO:0031529 ISS ruffle organization
GO:0032403 IEA protein complex binding
GO:0043005 IDA neuron projection
GO:0045202 IEA synapse
GO:0048365 ISS Rac GTPase binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048675 ISS axon extension
GO:0050890 IEA cognition
GO:0051015 ISS actin filament binding
GO:0070062 IEA extracellular vesicular exosome
GO:2000601 IEA positive regulation of Arp2/3 complex-mediated actin nucleation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044345 cyfip1 cytoplasmic FMR1 interacting protein 1 protein_coding Danio_rerio
ENSG00000273749 CYFIP1 cytoplasmic FMR1 interacting protein 1 protein_coding Homo_sapiens

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