C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: milk fat globule-EGF factor 8 protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030605 Mfge8 10090 - 7:79133769-79149060 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032825 Mfge8-201 79133769-79149060 protein_coding
  ENSMUST00000107409 Mfge8-202 79133769-79149060 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032825ENSMUST00000107409
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032825 29.312±1.09 N/A 17.371±0.39 N/A 54.144±1.91 9.108±1.25 N/A N/A 5.272±2.19 21.410±1.95 2.246±0.64 15.256±0.00 67.158±36.64 3.772±0.25
ENSMUST00000107409 170.244±47.12 214.282±4.92 58.745±1.86 50.611±11.02 261.320±108.12 72.559±6.78 61.357±8.87 76.307±1.98 20.072±13.98 170.555±10.91 17.932±2.55 204.465±59.21 122.005±43.90 27.127±11.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00011I CIL_00011I_0002 CGP 7:79117027-79149060
CIL_00011J CIL_00011J_0002 CGP 7:79133769-79365508

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001786 IDA phosphatidylserine binding
GO:0005178 IDA integrin binding
GO:0005615 IDA extracellular space
GO:0006910 IDA phagocytosis, recognition
GO:0006911 IDA phagocytosis, engulfment
GO:0007155 IEA cell adhesion
GO:0007338 IEA single fertilization
GO:0008429 IDA phosphatidylethanolamine binding
GO:0009897 IDA external side of plasma membrane
GO:0016020 IEA membrane
GO:0019897 IDA extrinsic component of plasma membrane
GO:0031012 IEA extracellular matrix
GO:0031982 IEA vesicle
GO:0050766 IDA positive regulation of phagocytosis
GO:0070062 IEA extracellular vesicular exosome
GO:2000427 IDA positive regulation of apoptotic cell clearance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015349 mfge8a milk fat globule-EGF factor 8 protein a protein_coding Danio_rerio
ENSDARG00000045803 mfge8b milk fat globule-EGF factor 8 protein b protein_coding Danio_rerio
ENSG00000140545 MFGE8 milk fat globule-EGF factor 8 protein protein_coding Homo_sapiens

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