C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: alpha thalassemia/mental retardation syndrome X-linked homolog (human)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031229 Atrx 10090 - X:105797615-105929397 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000101305 Atrx-004 105881958-105928577 protein_coding
  ENSMUST00000113573 Atrx-001 105797615-105929397 protein_coding
  ENSMUST00000123174 Atrx-005 105851437-105875264 retained_intron
  ENSMUST00000126345 Atrx-017 105911503-105929346 processed_transcript
  ENSMUST00000127221 Atrx-010 105818070-105826125 processed_transcript
  ENSMUST00000128968 Atrx-014 105875130-105889016 protein_coding
  ENSMUST00000130980 Atrx-016 105887781-105929397 protein_coding
  ENSMUST00000133543 Atrx-019 105878369-105880387 retained_intron
  ENSMUST00000134381 Atrx-015 105877241-105929206 protein_coding
  ENSMUST00000134507 Atrx-002 105876960-105929350 protein_coding
  ENSMUST00000137453 Atrx-013 105884356-105929367 protein_coding
  ENSMUST00000138765 Atrx-011 105801750-105803798 retained_intron
  ENSMUST00000141609 Atrx-009 105818096-105829646 processed_transcript
  ENSMUST00000142235 Atrx-007 105838379-105846957 retained_intron
  ENSMUST00000143361 Atrx-012 105800417-105802050 retained_intron
  ENSMUST00000146193 Atrx-006 105846737-105851524 retained_intron
  ENSMUST00000150914 Atrx-003 105876960-105929370 protein_coding
  ENSMUST00000154866 Atrx-018 105877441-105929315 protein_coding
  ENSMUST00000155445 Atrx-008 105838024-105839964 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000113573ENSMUST00000126345ENSMUST00000130980ENSMUST00000134507ENSMUST00000150914
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000113573 4.035±2.82 4.737±0.85 6.249±1.95 19.785±3.66 4.869±2.81 3.144±0.53 0.885±0.09 1.087±0.33 2.771±2.25 5.441±2.19 1.018±0.53 7.455±4.04 3.400±0.11 0.362±0.02
ENSMUST00000126345 40.362±3.72 21.939±3.04 N/A N/A 36.867±4.58 18.598±5.02 N/A 14.023±1.40 8.537±1.75 32.538±8.34 N/A 29.510±7.59 N/A N/A
ENSMUST00000130980 N/A 4.089±0.00 N/A N/A 8.002±0.00 3.988±0.00 N/A N/A N/A N/A N/A 9.808±1.88 N/A N/A
ENSMUST00000134507 N/A 2.454±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000150914 N/A 2.639±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001YN CIL_0001YN_0002 CGP X:105764279-105929397
CIL_0001YT CIL_0001YT_0002 CGP X:105797615-106011906

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000228 IDA nuclear chromosome
GO:0000792 IDA heterochromatin
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0004386 IEA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0006200 IEA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006334 ISS nucleosome assembly
GO:0006336 ISS DNA replication-independent nucleosome assembly
GO:0006338 ISS chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0007283 IMP spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0010571 IMP positive regulation of nuclear cell cycle DNA replication
GO:0015616 IEA DNA translocase activity
GO:0030330 IMP DNA damage response, signal transduction by p53 class mediator
GO:0030900 IMP forebrain development
GO:0031297 IMP replication fork processing
GO:0031933 IDA telomeric heterochromatin
GO:0032206 IMP positive regulation of telomere maintenance
GO:0035064 IEA methylated histone binding
GO:0042393 IDA histone binding
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0060009 IMP Sertoli cell development
GO:0070087 IEA chromo shadow domain binding
GO:0070603 ISS SWI/SNF superfamily-type complex
GO:0072520 IMP seminiferous tubule development
GO:0072711 IMP cellular response to hydroxyurea
GO:1901581 IMP negative regulation of telomeric RNA transcription from RNA pol II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042236 atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) protein_coding Danio_rerio
ENSG00000085224 ATRX alpha thalassemia/mental retardation syndrome X-linked protein_coding Homo_sapiens

Loading