C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: G protein-coupled receptor 124
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033876 Gpr124-001 ENSMUSG00000031486 10090 + 8:27085598-27123436 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033876
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033876 19.150±13.78 4.852±1.75 16.743±3.68 3.675±1.32 5.018±2.00 6.497±2.20 2.632±0.53 6.693±0.97 1.303±0.57 8.675±3.64 0.466±0.09 12.164±6.90 5.965±3.30 0.353±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000802 CIL_000802_0002 VISTA 8:26613996-27214881
CIL_0009C5 CIL_0009C5_0002 VISTA 8:26806327-27408431
CIL_0007QT CIL_0007QT_0002 VISTA 8:26806345-27408424
CIL_0002IW CIL_0002IW_0002 CGP 8:27042555-27123436
CIL_0002IX CIL_0002IX_0002 CGP 8:27085583-27128632

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0002040 IMP sprouting angiogenesis
GO:0004930 IEA G-protein coupled receptor activity
GO:0005886 ISO plasma membrane
GO:0007218 IEA neuropeptide signaling pathway
GO:0007417 IMP central nervous system development
GO:0009986 IDA cell surface
GO:0010595 IDA positive regulation of endothelial cell migration
GO:0016021 IEA integral component of membrane
GO:0043542 IMP endothelial cell migration
GO:0045765 IMP regulation of angiogenesis
GO:0050920 IMP regulation of chemotaxis
GO:0090210 IMP regulation of establishment of blood-brain barrier
GO:1900747 IMP negative regulation of vascular endothelial growth factor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000220659 BRF2-001 protein_coding Homo_sapiens 0 305
ENST00000315215 GPR124-002 protein_coding Homo_sapiens 0 2134
ENST00000412232 GPR124-001 protein_coding Homo_sapiens 0 3906
ENST00000428068 GPR124-004 protein_coding Homo_sapiens 0 531

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