C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NEDD8 activating enzyme E1 subunit 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031878 Nae1 10090 - 8:104511028-104534637 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034349 Nae1-001 104511028-104534637 protein_coding
  ENSMUST00000159330 Nae1-009 104511037-104518043 retained_intron
  ENSMUST00000159393 Nae1-002 104522905-104534588 retained_intron
  ENSMUST00000159696 Nae1-007 104519786-104523213 retained_intron
  ENSMUST00000159702 Nae1-005 104528030-104534614 retained_intron
  ENSMUST00000160148 Nae1-010 104513200-104517049 retained_intron
  ENSMUST00000160913 Nae1-003 104517537-104527915 retained_intron
  ENSMUST00000161411 Nae1-011 104511034-104516989 retained_intron
  ENSMUST00000161462 Nae1-008 104511028-104523181 processed_transcript
  ENSMUST00000161474 Nae1-006 104523334-104527334 retained_intron
  ENSMUST00000162466 Nae1-004 104511028-104534636 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034349ENSMUST00000159330ENSMUST00000159393ENSMUST00000159702ENSMUST00000160148ENSMUST00000160913ENSMUST00000161462ENSMUST00000162466
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034349 4.691±0.95 N/A 18.064±3.81 15.140±8.64 3.505±1.47 2.079±0.95 4.616±1.09 3.590±1.00 8.677±6.63 4.765±1.27 11.029±0.93 4.809±4.08 12.390±6.11 9.574±4.06
ENSMUST00000159330 N/A N/A N/A N/A N/A N/A 3.510±0.00 N/A N/A N/A N/A 1.120±0.00 N/A N/A
ENSMUST00000159393 0.675±0.24 0.371±0.17 2.228±0.57 2.438±0.00 0.442±0.02 N/A 0.420±0.03 0.380±0.00 0.603±0.32 0.997±0.21 N/A 0.939±0.56 0.988±0.00 1.038±0.00
ENSMUST00000159702 N/A 1.580±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000160148 4.097±1.57 0.966±0.35 N/A N/A 3.958±1.46 2.342±0.19 2.942±0.56 2.520±0.25 1.695±0.29 4.668±0.86 N/A 2.693±1.26 N/A N/A
ENSMUST00000160913 N/A 0.285±0.07 N/A 0.978±0.00 0.713±0.21 0.545±0.03 N/A N/A 0.380±0.00 N/A N/A 0.997±0.45 N/A 0.580±0.00
ENSMUST00000161462 N/A N/A N/A N/A N/A N/A N/A 2.309±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000162466 N/A 1.170±0.55 N/A 13.523±0.00 1.031±0.14 1.801±0.00 N/A 1.916±0.54 2.125±0.90 1.802±0.00 1.759±0.00 6.505±5.41 11.551±3.16 13.340±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WN CIL_0007WN_0002 VISTA 8:104309522-104912018
CIL_0004IV CIL_0004IV_0002 CGP 8:104446719-104534637
CIL_0003LY CIL_0003LY_0003 CGP 8:104511028-104550343

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IBA nucleus
GO:0005829 IBA cytosol
GO:0005886 IEA plasma membrane
GO:0019781 IBA NEDD8 activating enzyme activity
GO:0031625 IEA ubiquitin protein ligase binding
GO:0033314 IEA mitotic DNA replication checkpoint
GO:0042981 IEA regulation of apoptotic process
GO:0043523 IEA regulation of neuron apoptotic process
GO:0045116 IBA protein neddylation
GO:0046982 IEA protein heterodimerization activity
GO:0051402 IEA neuron apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011301 nae1 nedd8 activating enzyme E1 subunit 1 protein_coding Danio_rerio
ENSG00000159593 NAE1 NEDD8 activating enzyme E1 subunit 1 protein_coding Homo_sapiens

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