C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ceroid-lipofuscinosis, neuronal 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032245 Cln6 10090 + 9:62838785-62852006 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034776 Cln6-001 62838785-62852006 protein_coding
  ENSMUST00000124984 Cln6-004 62847033-62851162 protein_coding
  ENSMUST00000138276 Cln6-003 62846015-62850711 nonsense_mediated_decay
  ENSMUST00000141821 Cln6-002 62838792-62846018 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034776ENSMUST00000138276
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034776 14.834±5.53 23.752±1.01 12.190±0.69 3.015±1.21 17.482±0.70 26.076±2.76 8.751±2.19 28.033±1.55 7.531±5.96 17.535±0.81 6.155±0.40 21.843±7.25 27.855±16.98 31.680±15.53
ENSMUST00000138276 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.475±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003W4 CIL_0003W4_0002 CGP 9:62791832-62852006
CIL_0008FO CIL_0008FO_0002 VISTA 9:62808235-63410238
CIL_00098T CIL_00098T_0002 VISTA 9:62831587-63433435
CIL_0004FC CIL_0004FC_0003 CGP 9:62838785-62875918

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001573 ISS ganglioside metabolic process
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005783 ISS endoplasmic reticulum
GO:0005788 ISS endoplasmic reticulum lumen
GO:0007040 IMP lysosome organization
GO:0007042 ISS lysosomal lumen acidification
GO:0007601 IMP visual perception
GO:0008203 ISS cholesterol metabolic process
GO:0016020 IEA membrane
GO:0030203 ISS glycosaminoglycan metabolic process
GO:0031987 IMP locomotion involved in locomotory behavior
GO:0042803 ISS protein homodimerization activity
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044265 IMP cellular macromolecule catabolic process
GO:0045862 ISS positive regulation of proteolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077584 cln6a ceroid-lipofuscinosis, neuronal 6a protein_coding Danio_rerio
ENSDARG00000090002 cln6b ceroid-lipofuscinosis, neuronal 6b protein_coding Danio_rerio
ENSG00000128973 CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant protein_coding Homo_sapiens

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