C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin alpha 2b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034664 Itga2b 10090 - 11:102453297-102470122 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000103086 Itga2b-001 102453297-102469883 protein_coding
  ENSMUST00000124767 Itga2b-005 102461212-102461937 processed_transcript
  ENSMUST00000128752 Itga2b-010 102455839-102457320 processed_transcript
  ENSMUST00000130433 Itga2b-006 102457510-102460835 processed_transcript
  ENSMUST00000130757 Itga2b-003 102467800-102470122 processed_transcript
  ENSMUST00000131247 Itga2b-008 102457200-102458359 processed_transcript
  ENSMUST00000134735 Itga2b-009 102453304-102456190 processed_transcript
  ENSMUST00000145925 Itga2b-004 102466287-102466955 processed_transcript
  ENSMUST00000149519 Itga2b-002 102456472-102467199 processed_transcript
  ENSMUST00000151625 Itga2b-007 102455897-102458565 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000103086ENSMUST00000128752ENSMUST00000130433ENSMUST00000131247ENSMUST00000134735ENSMUST00000149519ENSMUST00000151625
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000103086 N/A N/A 0.616±0.00 0.900±0.00 3.122±0.68 0.401±0.20 1.052±0.58 0.780±0.25 8.107±8.21 2.940±0.44 0.109±0.06 0.673±0.00 1.819±0.86 0.547±0.00
ENSMUST00000128752 N/A 2.303±1.11 N/A N/A N/A N/A N/A N/A N/A N/A 0.477±0.00 3.409±0.63 N/A N/A
ENSMUST00000130433 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.946±2.63 0.635±0.00
ENSMUST00000131247 N/A N/A N/A N/A 3.042±0.00 N/A N/A N/A N/A N/A 0.265±0.00 1.138±0.28 N/A 0.712±0.00
ENSMUST00000134735 1.920±0.14 1.837±0.59 2.362±0.79 N/A N/A 1.157±0.20 N/A 3.026±0.45 N/A N/A 0.269±0.00 3.463±1.67 N/A 0.472±0.00
ENSMUST00000149519 0.482±0.00 0.335±0.00 N/A N/A N/A 0.255±0.00 0.106±0.00 N/A N/A N/A 0.148±0.07 0.719±0.29 0.206±0.00 N/A
ENSMUST00000151625 N/A N/A N/A N/A 5.967±0.00 N/A N/A 2.094±0.00 N/A N/A 0.239±0.10 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B6 CIL_0009B6_0002 VISTA 11:102063033-102664797
CIL_0007ST CIL_0007ST_0002 VISTA 11:102292756-102896210
CIL_0004D6 CIL_0004D6_0003 CGP 11:102436981-102470122
CIL_0005IZ CIL_0005IZ_0002 CGP 11:102453297-102556392

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002687 IEA positive regulation of leukocyte migration
GO:0005515 IEA protein binding
GO:0005925 IDA focal adhesion
GO:0007160 IMP cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008305 IEA integrin complex
GO:0009897 IDA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0042802 IEA identical protein binding
GO:0046872 IEA metal ion binding
GO:0050840 IMP extracellular matrix binding
GO:0070051 IEA fibrinogen binding
GO:0070062 IEA extracellular vesicular exosome
GO:0070527 IEA platelet aggregation
GO:0072562 IEA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018687 itga2b integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) protein_coding Danio_rerio
ENSG00000005961 ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) protein_coding Homo_sapiens

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