C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pre B cell leukemia homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034673 Pbx2 10090 + 17:34591266-34597400 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038149 Pbx2-001 34592263-34597400 protein_coding
  ENSMUST00000173229 Pbx2-004 34595460-34596227 retained_intron
  ENSMUST00000173328 Pbx2-002 34591266-34596607 protein_coding
  ENSMUST00000174532 Pbx2-003 34593395-34594383 protein_coding
  ENSMUST00000183827 Pbx2-005 34592734-34596416 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038149ENSMUST00000173229ENSMUST00000173328ENSMUST00000174532ENSMUST00000183827
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038149 7.105±2.91 10.149±4.90 8.281±1.00 9.507±4.41 5.501±2.21 8.111±0.80 2.424±0.35 6.336±0.64 4.915±2.30 9.971±0.89 3.069±0.49 7.537±2.05 9.923±3.07 0.985±0.33
ENSMUST00000173229 N/A N/A N/A 16.167±0.00 N/A N/A N/A N/A 6.021±0.00 N/A N/A 16.722±0.00 N/A N/A
ENSMUST00000173328 6.955±1.87 N/A 5.339±0.05 16.096±4.06 6.449±1.31 6.673±0.84 3.828±1.18 6.811±2.01 5.186±2.67 12.546±2.38 2.228±0.78 7.062±2.61 13.467±7.68 2.058±0.63
ENSMUST00000174532 N/A 15.339±3.87 N/A N/A N/A 18.421±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000183827 13.890±3.07 6.035±1.07 8.953±1.19 12.256±0.99 12.044±2.02 13.023±0.76 2.911±0.00 6.730±0.32 5.847±2.53 12.739±0.85 2.231±0.00 23.630±6.35 15.959±1.74 2.036±0.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002RT CIL_0002RT_0002 CGP 17:34589806-34597400

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003682 IDA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0008134 IEA transcription factor binding
GO:0009954 IGI proximal/distal pattern formation
GO:0030326 IGI embryonic limb morphogenesis
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019717 pbx2 pre-B-cell leukemia transcription factor 2 protein_coding Danio_rerio
ENSG00000204304 PBX2 pre-B-cell leukemia homeobox 2 protein_coding Homo_sapiens

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