C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: patatin-like phospholipase domain containing 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036257 Pnpla8 10090 + 12:44221370-44312343 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043082 Pnpla8-001 44269186-44312244 protein_coding
  ENSMUST00000122902 Pnpla8-002 44221370-44312092 protein_coding
  ENSMUST00000125757 Pnpla8-004 44275271-44282890 protein_coding
  ENSMUST00000143771 Pnpla8-003 44282573-44312343 protein_coding
  ENSMUST00000156082 Pnpla8-005 44299277-44311844 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043082ENSMUST00000122902ENSMUST00000143771ENSMUST00000156082
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043082 19.119±5.28 6.135±2.42 16.839±0.20 15.943±3.04 12.025±5.08 4.657±1.30 15.090±2.83 12.169±2.97 11.343±4.49 8.737±1.44 26.921±2.79 9.343±4.32 13.173±5.03 10.689±3.03
ENSMUST00000122902 N/A N/A N/A 6.710±0.00 N/A N/A N/A N/A N/A N/A N/A 7.113±0.00 3.957±0.00 1.614±0.00
ENSMUST00000143771 N/A N/A N/A 3.826±0.00 N/A N/A N/A N/A N/A N/A 3.824±0.00 6.140±0.24 5.646±0.00 N/A
ENSMUST00000156082 13.536±1.40 9.030±0.80 N/A N/A 12.186±2.00 4.276±0.97 N/A 7.463±0.29 7.149±0.65 8.177±1.38 N/A 8.484±2.44 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PF CIL_0008PF_0002 VISTA 12:44102519-44705770
CIL_0008CE CIL_0008CE_0002 VISTA 12:44102792-44705590
CIL_00057O CIL_00057O_0002 CGP 12:44221370-44601846

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001516 IEA prostaglandin biosynthetic process
GO:0004622 IEA lysophospholipase activity
GO:0005622 ISS intracellular
GO:0005777 IEA peroxisome
GO:0005778 ISS peroxisomal membrane
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0006629 IEA lipid metabolic process
GO:0006631 ISS fatty acid metabolic process
GO:0008219 IEA cell death
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019369 IEA arachidonic acid metabolic process
GO:0034638 IEA phosphatidylcholine catabolic process
GO:0043651 IEA linoleic acid metabolic process
GO:0046338 IEA phosphatidylethanolamine catabolic process
GO:0047499 ISS calcium-independent phospholipase A2 activity
GO:0050482 IEA arachidonic acid secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078745 pnpla8 patatin-like phospholipase domain containing 8 protein_coding Danio_rerio
ENSG00000135241 PNPLA8 patatin-like phospholipase domain containing 8 protein_coding Homo_sapiens

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