C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histocompatibility 2, class II antigen A, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036594 H2-Aa 10090 - 17:34282744-34287827 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000040655 H2-Aa-001 34282744-34287827 protein_coding
  ENSMUST00000165139 H2-Aa-003 34283772-34287777 retained_intron
  ENSMUST00000173944 H2-Aa-002 34286465-34287819 processed_transcript
  ENSMUST00000174751 H2-Aa-004 34282765-34287791 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000040655ENSMUST00000174751
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000040655 241.157±34.70 106.399±15.91 124.138±2.45 0.238±0.10 700.966±55.31 133.406±13.04 43.716±16.69 106.220±17.18 17.824±16.86 330.991±59.48 12.301±14.69 132.489±19.90 4.784±8.85 4.335±2.02
ENSMUST00000174751 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.599±6.32 63.662±2.93 0.482±0.16 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XS CIL_0002XS_0009 CGP 17:34263209-34287827
CIL_0001PL CIL_0001PL_000A CGP 17:34282744-34316199

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002474 IEA antigen processing and presentation of peptide antigen via MHC class I
GO:0005515 IPI protein binding
GO:0005764 IDA lysosome
GO:0005886 IDA plasma membrane
GO:0009897 IDA external side of plasma membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IDA antigen processing and presentation
GO:0019886 IDA antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0034341 IDA response to interferon-gamma
GO:0042605 IDA peptide antigen binding
GO:0042612 IEA MHC class I protein complex
GO:0042613 IDA MHC class II protein complex
GO:0045582 IDA positive regulation of T cell differentiation
GO:0048002 IDA antigen processing and presentation of peptide antigen

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001832 si:ch1073-403i13.1 si:ch1073-403i13.1 protein_coding Danio_rerio
ENSDARG00000020286 zgc:123107 zgc:123107 protein_coding Danio_rerio
ENSDARG00000031745 si:busm1-266f07.2 si:busm1-266f07.2 protein_coding Danio_rerio
ENSDARG00000053739 si:busm1-160c18.1 si:busm1-160c18.1 protein_coding Danio_rerio
ENSDARG00000055441 si:busm1-48c11.3 si:busm1-48c11.3 protein_coding Danio_rerio
ENSDARG00000070206 si:zfos-2070c2.1 si:zfos-2070c2.1 protein_coding Danio_rerio
ENSDARG00000074816 si:zfos-367g9.1 si:zfos-367g9.1 protein_coding Danio_rerio
ENSDARG00000075932 si:ch73-211l2.3 si:ch73-211l2.3 protein_coding Danio_rerio
ENSDARG00000079593 si:busm1-228j01.5 si:busm1-228j01.5 protein_coding Danio_rerio
ENSDARG00000086294 CU914776.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000196735 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 protein_coding Homo_sapiens

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