C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: histocompatibility 2, class II antigen A, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000040655 H2-Aa-001 ENSMUSG00000036594 10090 - 17:34282744-34287827 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000040655
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000040655 241.157±34.70 106.399±15.91 124.138±2.45 0.238±0.10 700.966±55.31 133.406±13.04 43.716±16.69 106.220±17.18 17.824±16.86 330.991±59.48 12.301±14.69 132.489±19.90 4.784±8.85 4.335±2.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XS CIL_0002XS_0009 CGP 17:34263209-34287827
CIL_0001PL CIL_0001PL_000A CGP 17:34282744-34316199

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005764 IDA lysosome
GO:0005886 IDA plasma membrane
GO:0009897 IDA external side of plasma membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IDA antigen processing and presentation
GO:0019886 IDA antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0034341 IDA response to interferon-gamma
GO:0042605 IDA peptide antigen binding
GO:0042613 IDA MHC class II protein complex
GO:0045582 IDA positive regulation of T cell differentiation
GO:0048002 IDA antigen processing and presentation of peptide antigen

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000343139 HLA-DQA1-001 protein_coding Homo_sapiens 0 608
ENST00000374949 HLA-DQA1-009 protein_coding Homo_sapiens 0 608
ENST00000395363 HLA-DQA1-004 protein_coding Homo_sapiens 0 608
ENST00000416403 HLA-DQA1-004 protein_coding Homo_sapiens 0 579
ENST00000442315 HLA-DQA1-004 protein_coding Homo_sapiens 0 579
ENST00000442680 HLA-DQA1-009 protein_coding Homo_sapiens 0 579
ENST00000443320 HLA-DQA1-001 protein_coding Homo_sapiens 0 579
ENST00000450960 HLA-DQA1-009 protein_coding Homo_sapiens 0 579
ENST00000451947 HLA-DQA1-005 protein_coding Homo_sapiens 0 579
ENST00000453504 HLA-DQA1-001 protein_coding Homo_sapiens 0 579
ENST00000457246 HLA-DQA1-005 protein_coding Homo_sapiens 0 579
ENST00000460633 HLA-DQA1-003 retained_intron Homo_sapiens 0 211
ENST00000461508 HLA-DQA1-002 nonsense_mediated_decay Homo_sapiens 0 525
ENST00000468299 HLA-DQA1-002 nonsense_mediated_decay Homo_sapiens 0 525
ENST00000476192 HLA-DQA1-003 retained_intron Homo_sapiens 0 195
ENST00000482745 HLA-DQA1-002 nonsense_mediated_decay Homo_sapiens 0 568
ENST00000497426 HLA-DQA1-003 retained_intron Homo_sapiens 0 195

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