C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cylindromatosis (turban tumor syndrome)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036712 Cyld 10090 + 8:88697028-88751945 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043526 Cyld-201 88697028-88751945 protein_coding
  ENSMUST00000098519 Cyld-202 88705222-88751945 protein_coding
  ENSMUST00000109626 Cyld-203 88705222-88751945 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043526ENSMUST00000098519ENSMUST00000109626
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043526 1.923±0.32 1.314±0.00 0.520±0.00 N/A N/A 0.471±0.10 0.586±0.00 1.062±0.00 0.491±0.03 N/A N/A N/A 1.069±0.00 0.371±0.17
ENSMUST00000098519 N/A 4.784±0.00 N/A 12.567±0.00 N/A N/A N/A N/A 0.252±0.00 N/A 1.266±0.25 1.643±0.81 N/A N/A
ENSMUST00000109626 1.728±0.45 3.245±1.03 3.043±0.00 7.995±0.00 1.058±0.22 2.118±0.93 1.227±0.00 N/A 1.089±0.50 1.244±0.00 1.867±0.35 2.606±1.92 3.674±2.12 3.234±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ON CIL_0007ON_0003 UCNEbase 8:88447800-92743752
CIL_00090I CIL_00090I_0002 VISTA 8:88457981-89059109
CIL_00085B CIL_00085B_0002 VISTA 8:88474689-89076074
CIL_00090J CIL_00090J_0002 VISTA 8:88479183-89079972
CIL_00090K CIL_00090K_0002 VISTA 8:88577161-89178261
CIL_00090L CIL_00090L_0002 VISTA 8:88581293-89181923
CIL_00090M CIL_00090M_0002 VISTA 8:88602694-89203557
CIL_00090N CIL_00090N_0002 VISTA 8:88624827-89225618
CIL_0008AU CIL_0008AU_0002 VISTA 8:88639020-89240224
CIL_0003PR CIL_0003PR_0002 CGP 8:88647315-88751945
CIL_0008AT CIL_0008AT_0002 VISTA 8:88673175-89274114
CIL_0008AL CIL_0008AL_0002 VISTA 8:88691555-89292644
CIL_00077S CIL_00077S_0002 CGP 8:88697028-89044162

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004843 ISS ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005813 IEA centrosome
GO:0005829 IBA cytosol
GO:0005881 ISS cytoplasmic microtubule
GO:0005886 IEA plasma membrane
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007346 IBA regulation of mitotic cell cycle
GO:0008270 ISS zinc ion binding
GO:0016055 IEA Wnt signaling pathway
GO:0016579 IMP protein deubiquitination
GO:0019901 IEA protein kinase binding
GO:0030496 ISS midbody
GO:0031234 IEA extrinsic component of cytoplasmic side of plasma membrane
GO:0032088 IBA negative regulation of NF-kappaB transcription factor activity
GO:0042347 ISS negative regulation of NF-kappaB import into nucleus
GO:0045581 IDA negative regulation of T cell differentiation
GO:0061578 IBA Lys63-specific deubiquitinase activity
GO:0070064 IEA proline-rich region binding
GO:0070266 IGI necroptotic process
GO:0070507 IEA regulation of microtubule cytoskeleton organization
GO:0070536 IBA protein K63-linked deubiquitination
GO:0090090 ISS negative regulation of canonical Wnt signaling pathway
GO:1901026 IMP ripoptosome assembly involved in necroptotic process
GO:2001238 IBA positive regulation of extrinsic apoptotic signaling pathway
GO:2001242 IBA regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060058 cylda cylindromatosis (turban tumor syndrome), a protein_coding Danio_rerio
ENSG00000083799 CYLD cylindromatosis (turban tumor syndrome) protein_coding Homo_sapiens

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