C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037685 Atp8a1 10090 - 5:67618140-67847432 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037380 Atp8a1-001 67618140-67847432 protein_coding
  ENSMUST00000072971 Atp8a1-002 67621721-67847369 protein_coding
  ENSMUST00000113651 Atp8a1-006 67780879-67847431 protein_coding
  ENSMUST00000113652 Atp8a1-004 67780879-67847431 protein_coding
  ENSMUST00000128726 Atp8a1-009 67812168-67815239 retained_intron
  ENSMUST00000130652 Atp8a1-008 67776168-67815229 processed_transcript
  ENSMUST00000135930 Atp8a1-003 67622599-67847206 protein_coding
  ENSMUST00000141443 Atp8a1-007 67812172-67815853 protein_coding
  ENSMUST00000143013 Atp8a1-010 67786281-67847429 retained_intron
  ENSMUST00000149501 Atp8a1-012 67622680-67660034 processed_transcript
  ENSMUST00000152433 Atp8a1-011 67766635-67769117 retained_intron
  ENSMUST00000155911 Atp8a1-005 67682142-67776759 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000037380ENSMUST00000072971ENSMUST00000113651ENSMUST00000113652ENSMUST00000135930ENSMUST00000143013
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000037380 0.513±0.00 1.706±0.07 5.947±0.51 5.193±0.55 5.421±0.79 2.864±0.38 N/A 0.995±0.60 42.225±0.00 6.972±3.39 2.660±0.86 N/A
ENSMUST00000072971 N/A N/A N/A N/A N/A N/A 1.531±0.00 N/A N/A N/A 1.410±0.00 0.232±0.00
ENSMUST00000113651 N/A 52.775±10.91 N/A N/A 20.000±2.92 N/A N/A 0.924±0.51 75.687±0.00 N/A 22.243±10.45 N/A
ENSMUST00000113652 N/A 45.768±14.48 N/A N/A N/A N/A N/A 1.175±0.31 N/A N/A 11.616±3.86 N/A
ENSMUST00000135930 N/A N/A 8.289±0.00 N/A N/A N/A N/A N/A N/A N/A 1.723±0.00 0.600±0.24
ENSMUST00000143013 N/A 9.858±0.00 N/A 17.456±0.00 16.693±0.00 N/A N/A N/A N/A N/A 12.682±7.87 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007OI CIL_0007OI_0002 UCNEbase 5:67098377-67633824
CIL_0007YP CIL_0007YP_0002 VISTA 5:67123705-67724669
CIL_0002Z3 CIL_0002Z3_0002 CGP 5:67392147-67623552
CIL_0002Z0 CIL_0002Z0_0002 CGP 5:67607883-67847432

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004012 IEA phospholipid-translocating ATPase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0007612 IMP learning
GO:0008152 IEA metabolic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019829 IEA cation-transporting ATPase activity
GO:0030335 IMP positive regulation of cell migration
GO:0031410 IEA cytoplasmic vesicle
GO:0045332 IEA phospholipid translocation
GO:0061092 IDA positive regulation of phospholipid translocation
GO:0070062 IEA extracellular vesicular exosome
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063001 atp8a1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 protein_coding Danio_rerio
ENSG00000124406 ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 protein_coding Homo_sapiens

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