C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific methyltransferase 2C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038056 Kmt2c 10090 - 5:25271798-25498783 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045291 Kmt2c-001 25273609-25498745 protein_coding
  ENSMUST00000172556 Kmt2c-008 25272426-25308550 protein_coding
  ENSMUST00000172626 Kmt2c-005 25382632-25498783 retained_intron
  ENSMUST00000172707 Kmt2c-009 25275651-25281400 retained_intron
  ENSMUST00000173073 Kmt2c-007 25315737-25498702 protein_coding
  ENSMUST00000173174 Kmt2c-003 25372836-25498755 protein_coding
  ENSMUST00000173673 Kmt2c-010 25289120-25293379 retained_intron
  ENSMUST00000174734 Kmt2c-006 25271798-25300075 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045291ENSMUST00000172556ENSMUST00000173073ENSMUST00000174734
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045291 1.428±0.52 1.180±0.44 N/A 2.493±0.00 1.606±0.61 1.735±0.62 0.889±0.00 1.096±0.00 0.286±0.05 2.002±0.17 N/A 3.194±1.64 3.154±1.45 0.729±0.21
ENSMUST00000172556 3.832±0.75 4.189±0.84 3.443±0.10 6.235±2.86 5.556±0.65 4.627±0.32 2.312±0.44 3.053±0.40 1.540±0.42 5.090±0.61 1.138±0.00 4.438±1.00 2.779±0.52 1.661±0.10
ENSMUST00000173073 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.587±0.00
ENSMUST00000174734 N/A N/A 3.420±0.34 3.386±1.71 N/A N/A N/A N/A 0.852±0.38 N/A 1.094±0.17 2.601±0.51 3.081±0.47 0.835±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007T7 CIL_0007T7_0002 VISTA 5:24699254-25303507
CIL_0007T1 CIL_0007T1_0002 VISTA 5:24708595-25311977
CIL_00027A CIL_00027A_0002 CGP 5:25222882-25498783

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005634 ISO nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016571 IDA histone methylation
GO:0035097 ISO histone methyltransferase complex
GO:0035556 IEA intracellular signal transduction
GO:0042800 ISO histone methyltransferase activity (H3-K4 specific)
GO:0044822 IEA poly(A) RNA binding
GO:0051568 IEA histone H3-K4 methylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075560 kmt2cb lysine (K)-specific methyltransferase 2Cb protein_coding Danio_rerio
ENSDARG00000079312 kmt2ca lysine (K)-specific methyltransferase 2Ca protein_coding Danio_rerio
ENSG00000055609 KMT2C lysine (K)-specific methyltransferase 2C protein_coding Homo_sapiens

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