C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholamban
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038583 Pln 10090 + 10:53337686-53345999 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000046221 Pln-201 53337686-53345999 protein_coding
  ENSMUST00000163319 Pln-202 53337686-53345999 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000046221ENSMUST00000163319
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000046221 2.559±1.72 0.274±0.07 2.569±0.42 0.090±0.04 0.469±0.18 6.712±1.09 1377.355±313.87 1.543±0.57 0.076±0.06 6.869±0.91 0.582±0.28 2.301±1.08 0.148±0.23 12.802±6.31
ENSMUST00000163319 N/A N/A N/A N/A N/A N/A N/A 0.228±0.00 N/A 0.730±0.00 0.146±0.03 0.767±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005XE CIL_0005XE_0002 CGP 10:52690533-53379851
CIL_000991 CIL_000991_0002 VISTA 10:53043568-53644849
CIL_0005XF CIL_0005XF_0002 CGP 10:53278081-53379851

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002026 IGI regulation of the force of heart contraction
GO:0005246 IEA calcium channel regulator activity
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0006874 IGI cellular calcium ion homeostasis
GO:0008016 IMP regulation of heart contraction
GO:0010043 IEA response to zinc ion
GO:0010459 IEA negative regulation of heart rate
GO:0010880 IMP regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 IMP regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0016529 IDA sarcoplasmic reticulum
GO:0031982 IEA vesicle
GO:0032868 IEA response to insulin
GO:0033574 IEA response to testosterone
GO:0043234 IEA protein complex
GO:0045822 IGI negative regulation of heart contraction
GO:0048738 IGI cardiac muscle tissue development
GO:0051260 IEA protein homooligomerization
GO:0051924 ISS regulation of calcium ion transport
GO:0051926 IEA negative regulation of calcium ion transport
GO:0060314 IMP regulation of ryanodine-sensitive calcium-release channel activity
GO:0086004 IMP regulation of cardiac muscle cell contraction
GO:0086023 IMP adrenergic receptor signaling pathway involved in heart process
GO:0086092 IMP regulation of the force of heart contraction by cardiac conduction
GO:0090279 IMP regulation of calcium ion import
GO:0090534 IEA calcium ion-transporting ATPase complex
GO:1901077 IMP regulation of relaxation of muscle
GO:1901894 IEA regulation of calcium-transporting ATPase activity
GO:1901895 IEA negative regulation of calcium-transporting ATPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000198523 PLN phospholamban protein_coding Homo_sapiens

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