C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cathepsin S
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038642 Ctss 10090 + 3:95526786-95556403 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000015667 Ctss-001 95526786-95556400 protein_coding
  ENSMUST00000116304 Ctss-201 95526786-95556403 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000015667ENSMUST00000116304
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000015667 3.281±1.06 N/A N/A N/A 4.599±0.00 8.169±1.28 0.774±0.00 1.081±0.19 1.200±0.26 N/A 0.582±0.08 2.369±1.68 N/A 0.336±0.21
ENSMUST00000116304 26.465±11.26 10.841±1.95 22.079±0.76 23.339±29.68 39.294±3.42 62.497±5.94 5.185±0.80 7.908±2.57 18.096±12.50 58.270±5.74 2.677±2.92 24.723±31.77 10.324±10.52 1.142±0.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00053K CIL_00053K_0002 CGP 3:95499286-95556403

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001968 IEA fibronectin binding
GO:0002250 IEA adaptive immune response
GO:0004197 IEA cysteine-type endopeptidase activity
GO:0005518 IEA collagen binding
GO:0005615 IEA extracellular space
GO:0005764 IDA lysosome
GO:0006508 IDA proteolysis
GO:0008233 IDA peptidase activity
GO:0008234 IEA cysteine-type peptidase activity
GO:0016020 IDA membrane
GO:0030574 IEA collagen catabolic process
GO:0031905 TAS early endosome lumen
GO:0034769 IEA basement membrane disassembly
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043236 IEA laminin binding
GO:0043394 IEA proteoglycan binding
GO:0050729 IGI positive regulation of inflammatory response
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0097067 IEA cellular response to thyroid hormone stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013771 ctssb.2 cathepsin Sb, tandem duplicate 2 protein_coding Danio_rerio
ENSDARG00000074656 ctssb.1 cathepsin Sb, tandem duplicate 1 protein_coding Danio_rerio
ENSG00000163131 CTSS cathepsin S protein_coding Homo_sapiens

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