C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: intraflagellar transport 88
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040040 Ift88 10090 + 14:57424062-57517936 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000122063 Ift88-001 57424062-57517936 protein_coding
  ENSMUST00000139943 Ift88-004 57479646-57487611 retained_intron
  ENSMUST00000150296 Ift88-003 57424080-57439775 nonsense_mediated_decay
  ENSMUST00000154492 Ift88-002 57424106-57517936 retained_intron
  ENSMUST00000171682 Ift88-005 57444443-57477969 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000122063ENSMUST00000139943ENSMUST00000150296ENSMUST00000154492
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000122063 1.017±0.37 0.698±0.24 3.853±0.34 3.990±0.45 0.734±0.28 0.807±0.16 0.725±0.06 1.907±0.54 0.712±0.30 1.516±0.42 1.215±0.16 4.669±2.93 2.850±0.88 16.309±6.26
ENSMUST00000139943 2.374±0.32 N/A N/A N/A 1.375±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000150296 2.813±0.00 1.438±0.47 N/A N/A 1.590±0.01 1.106±0.30 1.097±0.53 2.631±0.24 0.848±0.03 2.995±0.96 N/A 3.678±0.96 N/A 12.733±0.22
ENSMUST00000154492 0.357±0.21 0.329±0.01 0.751±0.06 0.978±0.43 N/A 0.264±0.01 N/A 0.312±0.02 0.197±0.03 N/A N/A 0.807±0.11 0.418±0.15 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003SM CIL_0003SM_0002 CGP 14:57275034-57517936
CIL_0003SN CIL_0003SN_0002 CGP 14:57424062-57543165

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001654 IGI eye development
GO:0001822 IMP kidney development
GO:0001889 IMP liver development
GO:0002080 IDA acrosomal membrane
GO:0003382 IMP epithelial cell morphogenesis
GO:0005515 IPI protein binding
GO:0005813 IDA centrosome
GO:0005814 IDA centriole
GO:0005929 IDA cilium
GO:0005930 IDA axoneme
GO:0007219 IMP Notch signaling pathway
GO:0007224 IGI smoothened signaling pathway
GO:0007288 IMP sperm axoneme assembly
GO:0007290 IMP spermatid nucleus elongation
GO:0007368 IMP determination of left/right symmetry
GO:0007399 IMP nervous system development
GO:0007420 IMP brain development
GO:0007507 IGI heart development
GO:0008104 IMP protein localization
GO:0008544 IMP epidermis development
GO:0008589 IMP regulation of smoothened signaling pathway
GO:0009887 IMP organ morphogenesis
GO:0009952 IMP anterior/posterior pattern specification
GO:0009953 IMP dorsal/ventral pattern formation
GO:0019894 IPI kinesin binding
GO:0021513 IMP spinal cord dorsal/ventral patterning
GO:0021537 IMP telencephalon development
GO:0030324 IMP lung development
GO:0030992 IDA intraciliary transport particle B
GO:0031016 IMP pancreas development
GO:0031122 IMP cytoplasmic microtubule organization
GO:0031512 IDA motile primary cilium
GO:0031514 IEA motile cilium
GO:0032391 IDA photoreceptor connecting cilium
GO:0034405 IMP response to fluid shear stress
GO:0036064 IDA ciliary basal body
GO:0036334 IMP epidermal stem cell homeostasis
GO:0042384 IMP cilium assembly
GO:0042487 IMP regulation of odontogenesis of dentin-containing tooth
GO:0042733 IMP embryonic digit morphogenesis
GO:0043568 IMP positive regulation of insulin-like growth factor receptor signaling pathway
GO:0045177 IDA apical part of cell
GO:0045598 IMP regulation of fat cell differentiation
GO:0048853 IMP forebrain morphogenesis
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0055007 IMP cardiac muscle cell differentiation
GO:0060021 IGI palate development
GO:0060091 IDA kinocilium
GO:0060122 IGI inner ear receptor stereocilium organization
GO:0060173 IGI limb development
GO:0060271 IMP cilium morphogenesis
GO:0060411 IMP cardiac septum morphogenesis
GO:0060426 IMP lung vasculature development
GO:0060914 IMP heart formation
GO:0070613 IMP regulation of protein processing
GO:0072372 IDA primary cilium
GO:0090102 IGI cochlea development
GO:0097541 IDA axonemal basal plate
GO:0097542 IDA ciliary tip
GO:0097546 IDA ciliary base
GO:1902017 IMP regulation of cilium assembly
GO:2000785 IMP regulation of autophagic vacuole assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027234 ift88 intraflagellar transport 88 homolog protein_coding Danio_rerio
ENSG00000032742 IFT88 intraflagellar transport 88 protein_coding Homo_sapiens

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