C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000099512 Hlcs-201 ENSMUSG00000040820 10090 - 16:94129306-94287856 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000099512
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000099512 2.286±0.13 1.158±0.85 1.570±0.00 2.653±0.00 0.477±0.00 0.966±0.01 0.569±0.28 1.129±0.00 0.861±0.32 2.371±0.25 1.152±0.19 0.546±0.37

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006Z8 CIL_0006Z8_0002 CGP 16:94085260-94313563
CIL_0006ZF CIL_0006ZF_0002 CGP 16:94129195-94336935

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000785 ISS chromatin
GO:0004077 IEA biotin-[acetyl-CoA-carboxylase] ligase activity
GO:0004078 IEA biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity
GO:0004079 IEA biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity
GO:0004080 ISS biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity
GO:0005524 IEA ATP binding
GO:0005652 ISS nuclear lamina
GO:0005737 ISS cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 ISS cytosol
GO:0008283 ISS cell proliferation
GO:0009305 ISS protein biotinylation
GO:0009374 ISS biotin binding
GO:0016363 ISS nuclear matrix
GO:0016570 ISS histone modification
GO:0018271 ISS biotin-protein ligase activity
GO:0019899 ISS enzyme binding
GO:0042803 ISS protein homodimerization activity
GO:0070781 ISS response to biotin
GO:0071110 ISS histone biotinylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000336648 HLCS-001 protein_coding Homo_sapiens 0 1522
ENST00000399120 HLCS-002 protein_coding Homo_sapiens 0 1522
ENST00000612277 HLCS-201 protein_coding Homo_sapiens 0 1522

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