C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon regulatory factor 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041515 Irf8 10090 + 8:120736358-120756694 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047737 Irf8-001 120736358-120756694 protein_coding
  ENSMUST00000160388 Irf8-006 120745480-120753733 retained_intron
  ENSMUST00000160594 Irf8-007 120752209-120753711 processed_transcript
  ENSMUST00000160943 Irf8-004 120739990-120755204 protein_coding
  ENSMUST00000162001 Irf8-003 120738639-120755581 protein_coding
  ENSMUST00000162658 Irf8-005 120736385-120753478 protein_coding
  ENSMUST00000162775 Irf8-002 120736359-120743234 retained_intron

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HH CIL_0008HH_0002 VISTA 8:120216454-120817853
CIL_0000IY CIL_0000IY_0002 CGP 8:120668222-120756694
CIL_0008L5 CIL_0008L5_0002 VISTA 8:120702895-121303512
CIL_0000YG CIL_0000YG_0003 CGP 8:120736358-121088144

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000975 IEA regulatory region DNA binding
GO:0003677 IDA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006909 IMP phagocytosis
GO:0006955 IMP immune response
GO:0009617 IMP response to bacterium
GO:0030099 IMP myeloid cell differentiation
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0032735 IMP positive regulation of interleukin-12 production
GO:0042742 IMP defense response to bacterium
GO:0042832 IMP defense response to protozoan
GO:0044130 IMP negative regulation of growth of symbiont in host
GO:0045893 IPI positive regulation of transcription, DNA-templated
GO:0060261 IDA positive regulation of transcription initiation from RNA polymerase II promoter
GO:0071222 IMP cellular response to lipopolysaccharide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056407 irf8 interferon regulatory factor 8 protein_coding Danio_rerio
ENSG00000140968 IRF8 interferon regulatory factor 8 protein_coding Homo_sapiens

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