C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interferon regulatory factor 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000162658 Irf8-005 ENSMUSG00000041515 10090 + 8:120736385-120753478 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HH CIL_0008HH_0002 VISTA 8:120216454-120817853
CIL_0000IY CIL_0000IY_0002 CGP 8:120668222-120756694
CIL_0008L5 CIL_0008L5_0002 VISTA 8:120702895-121303512
CIL_0000YG CIL_0000YG_0003 CGP 8:120736358-121088144

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000975 IEA regulatory region DNA binding
GO:0003677 IDA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006909 IMP phagocytosis
GO:0006955 IMP immune response
GO:0009617 IMP response to bacterium
GO:0030099 IMP myeloid cell differentiation
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0032735 IMP positive regulation of interleukin-12 production
GO:0042742 IMP defense response to bacterium
GO:0042832 IMP defense response to protozoan
GO:0044130 IMP negative regulation of growth of symbiont in host
GO:0045893 IPI positive regulation of transcription, DNA-templated
GO:0060261 IDA positive regulation of transcription initiation from RNA polymerase II promoter
GO:0071222 IMP cellular response to lipopolysaccharide

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000268638 IRF8-001 protein_coding Homo_sapiens 0 285
ENST00000562492 IRF8-009 protein_coding Homo_sapiens 1.4013e-45 187
ENST00000564803 IRF8-006 protein_coding Homo_sapiens 0 285
ENST00000569145 IRF8-008 protein_coding Homo_sapiens 8e-34 147
ENST00000569607 IRF8-010 protein_coding Homo_sapiens 0 195

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