C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: src homology 2 domain-containing transforming protein B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000044813 Shb 10090 - 4:45423278-45532470 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000061986 Shb-001 45423278-45530330 protein_coding
  ENSMUST00000125599 Shb-006 45447506-45489403 retained_intron
  ENSMUST00000130107 Shb-004 45444706-45492841 processed_transcript
  ENSMUST00000146236 Shb-005 45458129-45489794 protein_coding
  ENSMUST00000147448 Shb-003 45458320-45532470 protein_coding
  ENSMUST00000147926 Shb-002 45423278-45482802 processed_transcript

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000061986ENSMUST00000125599ENSMUST00000146236ENSMUST00000147926
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000061986 6.339±0.97 31.324±5.54 12.211±0.50 8.376±4.31 7.912±1.10 14.503±1.46 5.923±0.64 18.793±3.50 9.216±5.09 13.249±1.66 1.120±0.17 10.194±4.19 7.732±4.16 2.316±1.09
ENSMUST00000125599 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.507±0.04 N/A N/A N/A
ENSMUST00000146236 N/A N/A N/A 9.402±0.00 N/A N/A N/A N/A N/A N/A N/A 12.193±0.00 25.841±4.17 3.094±0.00
ENSMUST00000147926 N/A N/A N/A N/A N/A N/A N/A N/A 8.817±2.71 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081A CIL_00081A_0002 VISTA 4:45205842-45807105
CIL_0006TM CIL_0006TM_0002 CGP 4:45395923-45532470
CIL_0006TL CIL_0006TL_0002 CGP 4:45423278-45804604

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001568 IMP blood vessel development
GO:0001948 IDA glycoprotein binding
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005575 ND cellular_component
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006469 IMP negative regulation of protein kinase activity
GO:0006915 IEA apoptotic process
GO:0009967 TAS positive regulation of signal transduction
GO:0030097 IMP hemopoiesis
GO:0030154 IEA cell differentiation
GO:0042100 IDA B cell proliferation
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0048514 IGI blood vessel morphogenesis
GO:0071425 IMP hematopoietic stem cell proliferation
GO:1900194 IMP negative regulation of oocyte maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000107338 SHB Src homology 2 domain containing adaptor protein B protein_coding Homo_sapiens
ENSG00000255872 RP11-613M10.9 protein_coding Homo_sapiens

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