C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: src homology 2 domain-containing transforming protein B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000061986 Shb-001 ENSMUSG00000044813 10090 - 4:45423278-45530330 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000061986
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000061986 6.339±0.97 31.324±5.54 12.211±0.50 8.376±4.31 7.912±1.10 14.503±1.46 5.923±0.64 18.793±3.50 9.216±5.09 13.249±1.66 1.120±0.17 10.194±4.19 7.732±4.16 2.316±1.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081A CIL_00081A_0002 VISTA 4:45205842-45807105
CIL_0006TM CIL_0006TM_0002 CGP 4:45395923-45532470
CIL_0006TL CIL_0006TL_0002 CGP 4:45423278-45804604

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001568 IMP blood vessel development
GO:0001948 IDA glycoprotein binding
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005575 ND cellular_component
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006469 IMP negative regulation of protein kinase activity
GO:0006915 IEA apoptotic process
GO:0009967 TAS positive regulation of signal transduction
GO:0030097 IMP hemopoiesis
GO:0030154 IEA cell differentiation
GO:0042100 IDA B cell proliferation
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0048514 IGI blood vessel morphogenesis
GO:0071425 IMP hematopoietic stem cell proliferation
GO:1900194 IMP negative regulation of oocyte maturation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000377707 SHB-001 protein_coding Homo_sapiens 0 2030
ENST00000540557 RP11-613M10.9-001 nonsense_mediated_decay Homo_sapiens 0 939

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