C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: high mobility group AT-hook 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000046711 Hmga1 10090 + 17:27556620-27563674 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000114888 Hmga1-002 27556623-27563668 protein_coding
  ENSMUST00000117254 Hmga1-004 27556668-27563060 protein_coding
  ENSMUST00000117600 Hmga1-001 27556620-27563674 protein_coding
  ENSMUST00000118570 Hmga1-003 27556668-27563663 protein_coding
  ENSMUST00000118599 Hmga1-005 27556658-27562491 protein_coding
  ENSMUST00000119486 Hmga1-006 27556641-27563025 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000114888ENSMUST00000117254ENSMUST00000117600ENSMUST00000118570ENSMUST00000118599ENSMUST00000119486
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000114888 3.946±0.32 N/A 10.126±2.23 7.152±3.02 5.663±1.23 12.196±1.88 3.312±1.09 2.869±0.51 26.006±30.13 3.575±0.37 6.192±1.66 2.619±0.81 23.003±16.14 2.977±1.42
ENSMUST00000117254 N/A 3.853±0.92 N/A 6.265±0.00 5.154±0.82 8.201±2.49 N/A 2.259±0.00 N/A 2.717±0.00 N/A 2.619±0.34 N/A 0.723±0.00
ENSMUST00000117600 1.595±0.23 N/A 6.271±1.39 17.835±5.25 4.305±0.53 N/A 5.304±0.43 3.315±1.50 20.465±17.00 3.880±0.95 4.075±1.21 2.742±0.61 21.426±2.59 7.912±1.29
ENSMUST00000118570 N/A 1.842±0.00 3.378±0.18 6.658±0.00 N/A 5.370±1.20 1.786±0.57 N/A 0.583±0.17 2.348±0.14 N/A 3.530±1.49 N/A 1.690±0.00
ENSMUST00000118599 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.382±1.59 N/A 80.890±0.00 N/A
ENSMUST00000119486 N/A N/A N/A N/A N/A 8.177±0.00 N/A N/A 21.326±3.22 N/A 6.947±1.38 N/A 12.792±4.94 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000251 CIL_000251_0002 CGP 17:27422387-27563674

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005634 ISS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008134 ISS transcription factor binding
GO:0008285 ISS negative regulation of cell proliferation
GO:0030374 ISS ligand-dependent nuclear receptor transcription coactivator activity
GO:0035985 ISS senescence-associated heterochromatin focus
GO:0035986 ISS senescence-associated heterochromatin focus assembly
GO:0042974 ISS retinoic acid receptor binding
GO:0042975 ISS peroxisome proliferator activated receptor binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046965 ISS retinoid X receptor binding
GO:0090402 ISS oncogene-induced cell senescence
GO:2000774 ISS positive regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028335 hmga1a high mobility group AT-hook 1a protein_coding Danio_rerio
ENSDARG00000070951 hmga1b high mobility group AT-hook 1b protein_coding Danio_rerio
ENSG00000137309 HMGA1 high mobility group AT-hook 1 protein_coding Homo_sapiens

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