C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: high mobility group AT-hook 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137309 HMGA1 9606 + 6:34236873-34246231 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000311487 HMGA1-004 34236873-34246231 protein_coding
  ENST00000347617 HMGA1-001 34236873-34246231 protein_coding
  ENST00000374116 HMGA1-201 34238791-34246230 protein_coding
  ENST00000401473 HMGA1-002 34236873-34246231 protein_coding
  ENST00000447654 HMGA1-202 34236873-34246230 protein_coding
  ENST00000478214 HMGA1-003 34237204-34245151 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000311487ENST00000347617ENST00000401473ENST00000447654ENST00000478214
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000311487 15.999±0.00 14.473±0.00 N/A 1.946±0.13 4.531±0.00 9.521±5.73 7.399±7.06 8.118±0.00 2.255±1.47 22.018±19.75 19.043±16.78 24.875±20.63 82.372±49.54 48.544±29.99
ENST00000347617 N/A N/A N/A N/A N/A 2.856±0.00 N/A N/A N/A N/A N/A 6.921±3.56 41.627±0.00 N/A
ENST00000401473 4.566±0.00 5.102±0.00 N/A 3.384±0.00 5.416±0.00 4.717±0.00 N/A 1.912±0.00 0.559±0.26 13.052±0.00 10.959±9.74 32.357±29.68 42.643±15.30 24.793±4.74
ENST00000447654 N/A N/A N/A N/A N/A N/A 0.290±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000478214 N/A N/A 0.543±0.00 N/A 2.330±0.00 N/A 0.377±0.00 N/A N/A N/A 2.058±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000251 CIL_000251_0001 CGP 6:34018645-34246231

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000737 IDA DNA catabolic process, endonucleolytic
GO:0003677 TAS:IEA DNA binding
GO:0003680 TAS AT DNA binding
GO:0003906 IDA DNA-(apurinic or apyrimidinic site) lyase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 TAS transcription factor complex
GO:0005829 TAS cytosol
GO:0005925 IDA focal adhesion
GO:0006268 NAS DNA unwinding involved in DNA replication
GO:0006284 IDA base-excision repair
GO:0006337 TAS nucleosome disassembly
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006461 TAS protein complex assembly
GO:0008134 IDA transcription factor binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0009615 IEP response to virus
GO:0016032 TAS viral process
GO:0019899 IPI enzyme binding
GO:0030374 IMP ligand-dependent nuclear receptor transcription coactivator activity
GO:0031936 TAS negative regulation of chromatin silencing
GO:0035985 IDA senescence-associated heterochromatin focus
GO:0035986 IDA senescence-associated heterochromatin focus assembly
GO:0042974 IDA retinoic acid receptor binding
GO:0042975 IDA peroxisome proliferator activated receptor binding
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0046965 IDA retinoid X receptor binding
GO:0051575 IDA 5'-deoxyribose-5-phosphate lyase activity
GO:0075713 TAS establishment of integrated proviral latency
GO:0090402 IDA oncogene-induced cell senescence
GO:2000774 IMP positive regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028335 hmga1a high mobility group AT-hook 1a protein_coding Danio_rerio
ENSDARG00000070951 hmga1b high mobility group AT-hook 1b protein_coding Danio_rerio
ENSMUSG00000046711 Hmga1 high mobility group AT-hook 1 protein_coding Mus_musculus
ENSMUSG00000078249 Hmga1-rs1 high mobility group AT-hook I, related sequence 1 protein_coding Mus_musculus

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