C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SET domain containing (lysine methyltransferase) 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049327 Setd8 10090 + 5:124439930-124462308 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000059580 Setd8-001 124439930-124462308 protein_coding
  ENSMUST00000100709 Setd8-002 124445493-124460883 protein_coding
  ENSMUST00000125588 Setd8-010 124451171-124460837 retained_intron
  ENSMUST00000134826 Setd8-004 124445784-124450879 retained_intron
  ENSMUST00000135667 Setd8-009 124450402-124459901 retained_intron
  ENSMUST00000138766 Setd8-005 124446704-124457118 processed_transcript
  ENSMUST00000143722 Setd8-008 124450171-124457118 processed_transcript
  ENSMUST00000147692 Setd8-007 124447005-124450784 processed_transcript
  ENSMUST00000147969 Setd8-003 124445505-124460977 processed_transcript
  ENSMUST00000154031 Setd8-006 124446962-124460631 processed_transcript

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000059580ENSMUST00000100709ENSMUST00000125588ENSMUST00000134826ENSMUST00000135667ENSMUST00000147692ENSMUST00000154031
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000059580 13.709±10.86 11.065±3.71 6.454±0.87 16.549±2.16 8.510±3.09 14.184±3.44 11.606±5.63 19.341±19.32 4.604±0.80 21.760±15.20 10.279±5.26 27.870±12.24 3.620±0.48
ENSMUST00000100709 7.774±0.00 8.325±1.16 5.621±0.00 4.807±0.00 N/A 15.549±2.99 N/A 1.935±0.34 N/A 11.711±1.44 11.358±1.22 12.911±0.00 N/A
ENSMUST00000125588 24.279±6.24 N/A N/A 10.093±0.00 16.257±1.25 N/A 16.289±0.52 38.807±0.00 9.771±0.00 N/A 16.825±0.00 27.112±0.00 4.144±0.22
ENSMUST00000134826 N/A 14.792±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000135667 N/A N/A N/A 17.910±0.00 N/A N/A N/A N/A N/A N/A 93.653±0.00 169.201±61.59 44.612±0.00
ENSMUST00000147692 N/A N/A N/A 50.848±0.00 N/A N/A N/A N/A N/A N/A 249.226±0.00 476.430±153.35 49.049±0.00
ENSMUST00000154031 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 32.722±2.27 89.729±18.54 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084E CIL_00084E_0002 VISTA 5:123871507-124476501
CIL_000665 CIL_000665_0002 CGP 5:124368702-124462308
CIL_0003J0 CIL_0003J0_0002 CGP 5:124439930-124478366

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0002039 IEA p53 binding
GO:0003714 IEA transcription corepressor activity
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0016279 IEA protein-lysine N-methyltransferase activity
GO:0018024 IEA histone-lysine N-methyltransferase activity
GO:0018026 IEA peptidyl-lysine monomethylation
GO:0034968 IEA histone lysine methylation
GO:0043516 IEA regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045892 IEA negative regulation of transcription, DNA-templated

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068319 setd8a SET domain containing (lysine methyltransferase) 8a protein_coding Danio_rerio
ENSDARG00000076551 setd8b SET domain containing (lysine methyltransferase) 8b protein_coding Danio_rerio
ENSG00000183955 SETD8 SET domain containing (lysine methyltransferase) 8 protein_coding Homo_sapiens

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