C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SET domain containing (lysine methyltransferase) 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000059580 Setd8-001 ENSMUSG00000049327 10090 + 5:124439930-124462308 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000059580
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000059580 13.709±10.86 11.065±3.71 6.454±0.87 16.549±2.16 8.510±3.09 14.184±3.44 11.606±5.63 19.341±19.32 4.604±0.80 21.760±15.20 10.279±5.26 27.870±12.24 3.620±0.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084E CIL_00084E_0002 VISTA 5:123871507-124476501
CIL_000665 CIL_000665_0002 CGP 5:124368702-124462308
CIL_0003J0 CIL_0003J0_0002 CGP 5:124439930-124478366

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0002039 IEA p53 binding
GO:0003714 IEA transcription corepressor activity
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0016279 IEA protein-lysine N-methyltransferase activity
GO:0018026 IEA peptidyl-lysine monomethylation
GO:0034968 IEA histone lysine methylation
GO:0043516 IEA regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045892 IEA negative regulation of transcription, DNA-templated

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000330479 SETD8-201 protein_coding Homo_sapiens 0 1493
ENST00000402868 SETD8-001 protein_coding Homo_sapiens 0 1493
ENST00000413684 AC027612.1-001 processed_pseudogene Homo_sapiens 0 1234
ENST00000437502 SETD8-005 protein_coding Homo_sapiens 0 937
ENST00000437519 SETD8-002 nonsense_mediated_decay Homo_sapiens 0 1210
ENST00000461103 SETD8-003 retained_intron Homo_sapiens 0 1020
ENST00000462311 SETD8-004 retained_intron Homo_sapiens 0 302
ENST00000478781 SETD8-007 processed_transcript Homo_sapiens 0 484
ENST00000485469 SETD8-006 processed_transcript Homo_sapiens 0 455
ENST00000623146 AL356585.3-201 pseudogene Homo_sapiens 0 1319

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