C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SET domain containing (lysine methyltransferase) 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000183955 SETD8 9606 + 12:123383773-123409358 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330479 SETD8-201 123383773-123409351 protein_coding
  ENST00000402868 SETD8-001 123383773-123409358 protein_coding
  ENST00000437502 SETD8-005 123390042-123407568 protein_coding
  ENST00000437519 SETD8-002 123384166-123408507 nonsense_mediated_decay
  ENST00000461103 SETD8-003 123389271-123405074 retained_intron
  ENST00000462311 SETD8-004 123389483-123391304 retained_intron
  ENST00000478781 SETD8-007 123388900-123396409 processed_transcript
  ENST00000485469 SETD8-006 123391380-123404918 processed_transcript
  ENST00000537270 SETD8-009 123384173-123388757 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330479ENST00000402868ENST00000437502ENST00000437519ENST00000461103ENST00000478781
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330479 N/A N/A N/A N/A N/A 0.667±0.00 N/A 0.580±0.00 0.307±0.00 N/A N/A 0.578±0.00 N/A N/A
ENST00000402868 1.324±0.00 3.070±0.00 N/A 3.057±0.00 2.347±0.00 1.355±0.00 1.213±0.91 1.094±0.00 0.462±0.09 1.213±0.49 1.367±0.00 4.899±1.46 3.920±0.73 3.635±1.85
ENST00000437502 N/A N/A N/A 1.913±0.00 N/A N/A 2.059±0.00 N/A 2.413±0.00 N/A 1.446±0.00 3.100±0.00 3.617±0.00 3.068±0.00
ENST00000437519 N/A N/A N/A 0.927±0.00 1.021±0.00 2.518±0.00 N/A 0.701±0.00 1.393±0.00 3.407±0.00 N/A 7.395±4.69 6.372±0.00 2.923±0.00
ENST00000461103 N/A N/A 0.630±0.00 3.178±0.00 N/A N/A N/A N/A N/A 1.527±0.00 N/A N/A 4.667±0.00 2.236±0.00
ENST00000478781 N/A N/A N/A N/A N/A N/A N/A N/A 2.889±0.00 N/A N/A 26.192±0.00 8.989±0.00 4.919±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000665 CIL_000665_0001 CGP 12:123289109-123409358
CIL_0003J0 CIL_0003J0_0001 CGP 12:123383773-123436717

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000278 TAS mitotic cell cycle
GO:0002039 IPI p53 binding
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005694 IEA chromosome
GO:0005730 IDA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0007067 IEA mitotic nuclear division
GO:0016279 IDA protein-lysine N-methyltransferase activity
GO:0018024 IDA:IEA histone-lysine N-methyltransferase activity
GO:0018026 IDA peptidyl-lysine monomethylation
GO:0034968 IEA histone lysine methylation
GO:0043516 IMP regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045892 IDA negative regulation of transcription, DNA-templated

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068319 setd8a SET domain containing (lysine methyltransferase) 8a protein_coding Danio_rerio
ENSDARG00000076551 setd8b SET domain containing (lysine methyltransferase) 8b protein_coding Danio_rerio
ENSMUSG00000049327 Setd8 SET domain containing (lysine methyltransferase) 8 protein_coding Mus_musculus

Loading