C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NLR family, CARD domain containing 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049871 Nlrc3 10090 - 16:3945007-3976632 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000096308 Nlrc3-002 3948870-3976632 retained_intron
  ENSMUST00000163478 Nlrc3-003 3948879-3964207 retained_intron
  ENSMUST00000177551 Nlrc3-004 3945610-3976632 protein_coding
  ENSMUST00000180200 Nlrc3-001 3945007-3976545 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000096308ENSMUST00000163478ENSMUST00000177551ENSMUST00000180200
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000096308 N/A N/A N/A N/A 1.228±0.00 N/A N/A N/A 0.075±0.00 N/A N/A 0.450±0.12 0.115±0.00 N/A
ENSMUST00000163478 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.299±0.07 0.373±0.18 N/A
ENSMUST00000177551 0.302±0.15 0.854±0.14 0.130±0.00 0.248±0.01 4.162±1.29 0.402±0.15 0.281±0.07 0.447±0.09 0.105±0.05 0.738±0.19 0.242±0.10 0.464±0.18 0.476±0.50 0.099±0.02
ENSMUST00000180200 0.237±0.06 3.254±1.41 0.173±0.00 0.785±0.03 3.064±1.68 0.678±0.00 0.383±0.22 0.378±0.09 0.208±0.14 0.557±0.06 0.862±0.37 3.084±1.93 0.777±0.26 0.388±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001DL CIL_0001DL_0002 CGP 16:3908801-3976632
CIL_0000AZ CIL_0000AZ_0002 CGP 16:3945007-4003770

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0007249 IEA I-kappaB kinase/NF-kappaB signaling
GO:0031396 IDA regulation of protein ubiquitination
GO:0032088 IEA negative regulation of NF-kappaB transcription factor activity
GO:0032496 IMP response to lipopolysaccharide
GO:0042110 IEA T cell activation
GO:0043124 IGI negative regulation of I-kappaB kinase/NF-kappaB signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061564 nlrc3 NLR family, CARD domain containing 3 protein_coding Danio_rerio
ENSG00000167984 NLRC3 NLR family, CARD domain containing 3 protein_coding Homo_sapiens

Loading