C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NLR family, CARD domain containing 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167984 NLRC3 9606 - 16:3539033-3577400 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324659 NLRC3-007 3541825-3577288 protein_coding
  ENST00000359128 NLRC3-001 3539033-3577391 protein_coding
  ENST00000448023 NLRC3-201 3539038-3565092 protein_coding
  ENST00000603055 NLRC3-006 3564070-3577373 processed_transcript
  ENST00000615877 NLRC3-002 3539038-3577400 nonsense_mediated_decay
  ENST00000618137 NLRC3-004 3548135-3556994 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastLungENST00000359128
Transcript ID Breast Lung
ENST00000359128 1.676±0.00 2.574±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005EX CIL_0005EX_0001 CGP 16:3493484-3539048
CIL_0001DL CIL_0001DL_0001 CGP 16:3500924-3577400
CIL_0000AZ CIL_0000AZ_0001 CGP 16:3539033-3611598

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0007249 IDA I-kappaB kinase/NF-kappaB signaling
GO:0031396 IEA regulation of protein ubiquitination
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032496 IEA response to lipopolysaccharide
GO:0042110 IEP T cell activation
GO:0043124 IMP negative regulation of I-kappaB kinase/NF-kappaB signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061564 nlrc3 NLR family, CARD domain containing 3 protein_coding Danio_rerio
ENSMUSG00000049871 Nlrc3 NLR family, CARD domain containing 3 protein_coding Mus_musculus

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