C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NLR family, CARD domain containing 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000177551 Nlrc3-004 ENSMUSG00000049871 10090 - 16:3945610-3976632 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000177551
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000177551 0.302±0.15 0.854±0.14 0.130±0.00 0.248±0.01 4.162±1.29 0.402±0.15 0.281±0.07 0.447±0.09 0.105±0.05 0.738±0.19 0.242±0.10 0.464±0.18 0.476±0.50 0.099±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001DL CIL_0001DL_0002 CGP 16:3908801-3976632
CIL_0000AZ CIL_0000AZ_0002 CGP 16:3945007-4003770

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0007249 IEA I-kappaB kinase/NF-kappaB signaling
GO:0031396 IDA regulation of protein ubiquitination
GO:0032088 IEA negative regulation of NF-kappaB transcription factor activity
GO:0032496 IMP response to lipopolysaccharide
GO:0042110 IEA T cell activation
GO:0043124 IGI negative regulation of I-kappaB kinase/NF-kappaB signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000324659 NLRC3-007 protein_coding Homo_sapiens 0 2621
ENST00000359128 NLRC3-001 protein_coding Homo_sapiens 0 2621
ENST00000448023 NLRC3-201 protein_coding Homo_sapiens 0 2621
ENST00000615877 NLRC3-002 nonsense_mediated_decay Homo_sapiens 0 1724
ENST00000618137 NLRC3-004 protein_coding Homo_sapiens 0 418

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