C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 8 (sodium/calcium exchanger), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054640 Slc8a1 10090 - 17:81388691-81649607 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086538 Slc8a1-201 81388691-81649607 protein_coding
  ENSMUST00000163123 Slc8a1-202 81388691-81649607 protein_coding
  ENSMUST00000163680 Slc8a1-203 81388691-81649607 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086538ENSMUST00000163123ENSMUST00000163680
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086538 N/A 0.009±0.00 1.277±0.00 1.315±0.00 N/A N/A 14.297±4.60 N/A 0.071±0.00 N/A 0.983±0.21 N/A N/A 0.672±0.00
ENSMUST00000163123 4.674±0.00 0.065±0.03 3.669±0.00 6.567±0.00 1.275±0.00 2.293±0.00 N/A 4.237±0.44 0.170±0.09 1.002±0.00 N/A N/A 0.409±0.12 0.611±0.07
ENSMUST00000163680 N/A 0.291±0.19 N/A N/A N/A 2.506±0.76 N/A 3.205±0.00 0.013±0.00 2.620±0.00 N/A 3.562±2.05 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00066Z CIL_00066Z_0002 CGP 17:81026327-81649607

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001892 IMP embryonic placenta development
GO:0002026 IMP regulation of the force of heart contraction
GO:0003007 IGI heart morphogenesis
GO:0005432 IDA calcium:sodium antiporter activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006814 IDA sodium ion transport
GO:0006816 IDA calcium ion transport
GO:0006883 IEA cellular sodium ion homeostasis
GO:0007154 IEA cell communication
GO:0008092 IEA cytoskeletal protein binding
GO:0009791 IGI post-embryonic development
GO:0016020 IDA membrane
GO:0016021 TAS integral component of membrane
GO:0016323 IDA basolateral plasma membrane
GO:0030315 IDA T-tubule
GO:0034614 IEA cellular response to reactive oxygen species
GO:0035050 IMP embryonic heart tube development
GO:0035725 IEA sodium ion transmembrane transport
GO:0042383 IDA sarcolemma
GO:0048747 IGI muscle fiber development
GO:0055013 IMP cardiac muscle cell development
GO:0060048 IGI cardiac muscle contraction
GO:0070509 IEA calcium ion import
GO:0071436 IEA sodium ion export
GO:0097369 IEA sodium ion import
GO:1901660 IEA calcium ion export

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013422 slc8a1a solute carrier family 8 (sodium/calcium exchanger), member 1a protein_coding Danio_rerio
ENSDARG00000043406 slc8a1b solute carrier family 8 (sodium/calcium exchanger), member 1b protein_coding Danio_rerio
ENSG00000183023 SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 protein_coding Homo_sapiens

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