C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ryanodine receptor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000057378 Ryr3 10090 - 2:112631355-113217096 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000080673 Ryr3-001 112631380-113217051 protein_coding
  ENSMUST00000091818 Ryr3-201 112631380-113030331 protein_coding
  ENSMUST00000128192 Ryr3-006 112996535-113217096 retained_intron
  ENSMUST00000134358 Ryr3-002 112632046-113217068 processed_transcript
  ENSMUST00000137131 Ryr3-005 112631355-112652758 processed_transcript
  ENSMUST00000142537 Ryr3-007 112636628-112640559 processed_transcript
  ENSMUST00000146187 Ryr3-004 112859286-112908497 retained_intron
  ENSMUST00000156757 Ryr3-003 112965849-113217062 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartLungMuscleOvaryPlacentaTestisENSMUST00000080673ENSMUST00000091818ENSMUST00000134358ENSMUST00000137131
Transcript ID Adipose Bladder Brain Breast Colon Heart Lung Muscle Ovary Placenta Testis
ENSMUST00000080673 N/A N/A 0.636±0.00 N/A 0.417±0.00 0.162±0.04 0.105±0.00 0.123±0.02 0.427±0.00 N/A N/A
ENSMUST00000091818 N/A N/A 0.674±0.13 N/A 0.266±0.12 0.126±0.00 0.085±0.00 0.174±0.00 0.404±0.00 N/A N/A
ENSMUST00000134358 0.841±0.33 N/A N/A N/A 0.323±0.19 0.172±0.00 0.156±0.00 N/A 0.449±0.19 N/A N/A
ENSMUST00000137131 2.444±0.02 7.893±0.78 5.323±1.91 0.649±0.00 N/A N/A N/A 0.369±0.00 0.739±0.03 0.895±0.00 16.000±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003HM CIL_0003HM_0002 CGP 2:112479171-112634573
CIL_000222 CIL_000222_0002 CGP 2:112492964-113217096

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005219 ISS ryanodine-sensitive calcium-release channel activity
GO:0005509 IEA calcium ion binding
GO:0005516 IEA calmodulin binding
GO:0005783 IEA endoplasmic reticulum
GO:0006816 IEA calcium ion transport
GO:0006874 IMP cellular calcium ion homeostasis
GO:0006941 IMP striated muscle contraction
GO:0015278 IEA calcium-release channel activity
GO:0016021 ISS integral component of membrane
GO:0030314 IDA junctional membrane complex
GO:0033017 IDA sarcoplasmic reticulum membrane
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048763 IEA calcium-induced calcium release activity
GO:0051289 ISS protein homotetramerization
GO:0051481 IEA negative regulation of cytosolic calcium ion concentration
GO:0070588 ISS calcium ion transmembrane transport
GO:0071277 ISS cellular response to calcium ion
GO:0071286 ISS cellular response to magnesium ion
GO:0071313 ISS cellular response to caffeine
GO:0071318 ISS cellular response to ATP

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042531 ryanodine receptor 3 protein_coding Danio_rerio
ENSDARG00000071331 ryr3 ryanodine receptor 3 protein_coding Danio_rerio
ENSDARG00000089493 ryanodine receptor 3 protein_coding Danio_rerio
ENSG00000198838 RYR3 ryanodine receptor 3 protein_coding Homo_sapiens

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