C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: speckle-type POZ protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000057522 Spop 10090 + 11:95414080-95493406 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000107722 Spop-001 95414098-95493406 protein_coding
  ENSMUST00000107724 Spop-002 95414080-95493406 protein_coding
  ENSMUST00000127713 Spop-004 95414243-95474335 protein_coding
  ENSMUST00000150884 Spop-003 95414095-95474314 protein_coding
  ENSMUST00000150922 Spop-005 95474319-95490315 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000107722ENSMUST00000107724
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000107722 13.656±5.62 29.495±2.74 28.992±4.24 8.405±3.81 20.802±6.50 26.558±3.74 42.790±12.13 16.918±6.01 17.209±6.19 46.483±22.56 61.186±8.66 20.447±5.96 7.440±4.47 7.846±4.72
ENSMUST00000107724 N/A N/A N/A 25.385±0.00 N/A N/A N/A N/A N/A N/A N/A 11.912±6.52 7.214±2.87 1.182±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QJ CIL_0007QJ_0002 VISTA 11:95039208-95641127
CIL_000877 CIL_000877_0002 VISTA 11:95055809-95658196
CIL_0009BV CIL_0009BV_0002 VISTA 11:95055825-95658170

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0016607 IDA nuclear speck
GO:0031463 ISS Cul3-RING ubiquitin ligase complex
GO:0031625 IEA ubiquitin protein ligase binding
GO:0042593 IGI glucose homeostasis
GO:0042787 IDA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161 IGI:ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1902237 IGI positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:2000676 IGI positive regulation of type B pancreatic cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038215 spop speckle-type POZ protein protein_coding Danio_rerio
ENSG00000121067 SPOP speckle-type POZ protein protein_coding Homo_sapiens

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