C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neurotrophic tyrosine kinase, receptor, type 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000059146 Ntrk3 10090 - 7:78192362-78578408 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039431 Ntrk3-001 78192362-78578408 protein_coding
  ENSMUST00000039438 Ntrk3-002 78302323-78577975 protein_coding
  ENSMUST00000151885 Ntrk3-004 78302323-78377822 processed_transcript
  ENSMUST00000155795 Ntrk3-003 78449625-78577975 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039431ENSMUST00000039438ENSMUST00000151885
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039431 N/A 4.706±1.66 N/A 4.058±0.00 0.203±0.11 0.236±0.00 0.927±0.00 0.041±0.02 0.712±0.02 0.120±0.01 2.390±0.51 0.058±0.02 0.079±0.00
ENSMUST00000039438 2.250±0.46 5.019±1.72 6.071±0.00 8.039±1.68 0.623±0.24 1.153±0.60 1.488±0.68 0.120±0.10 2.059±0.43 0.142±0.06 6.202±2.02 0.074±0.04 1.328±0.02
ENSMUST00000151885 N/A N/A N/A N/A N/A N/A N/A 0.119±0.02 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000NY CIL_0000NY_0002 CGP 7:76318072-78578408
CIL_0001AZ CIL_0001AZ_0002 CGP 7:78192362-78783531

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0001764 IEA neuron migration
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0002039 IEA p53 binding
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005030 IEA neurotrophin receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007623 IEP circadian rhythm
GO:0008284 IEA positive regulation of cell proliferation
GO:0010628 IEA positive regulation of gene expression
GO:0016020 IEA membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019056 IEA modulation by virus of host transcription
GO:0030335 IEA positive regulation of cell migration
GO:0032148 IEA activation of protein kinase B activity
GO:0032856 IEA activation of Ras GTPase activity
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0038179 IEA neurotrophin signaling pathway
GO:0042490 IMP mechanoreceptor differentiation
GO:0043235 ISO receptor complex
GO:0045471 IEA response to ethanol
GO:0046777 IEA protein autophosphorylation
GO:0046875 IEA ephrin receptor binding
GO:0048665 IEA neuron fate specification
GO:0048678 IEA response to axon injury
GO:0048691 IGI positive regulation of axon extension involved in regeneration
GO:0048712 IEA negative regulation of astrocyte differentiation
GO:0050927 IEA positive regulation of positive chemotaxis
GO:0051412 IEA response to corticosterone
GO:0060548 IEA negative regulation of cell death
GO:0070306 IGI lens fiber cell differentiation
GO:0071300 IEA cellular response to retinoic acid
GO:0090102 IEA cochlea development
GO:2000251 IEA positive regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063035 ntrk3b neurotrophic tyrosine kinase, receptor, type 3b protein_coding Danio_rerio
ENSDARG00000077228 ntrk3a neurotrophic tyrosine kinase, receptor, type 3a protein_coding Danio_rerio
ENSG00000140538 NTRK3 neurotrophic tyrosine kinase, receptor, type 3 protein_coding Homo_sapiens

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