C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: neurotrophic tyrosine kinase, receptor, type 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000039431 Ntrk3-001 ENSMUSG00000059146 10090 - 7:78192362-78578408 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039431
Transcript ID Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039431 4.706±1.66 4.058±0.00 0.203±0.11 0.236±0.00 0.927±0.00 0.041±0.02 0.712±0.02 0.120±0.01 2.390±0.51 0.058±0.02 0.079±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000NY CIL_0000NY_0002 CGP 7:76318072-78578408
CIL_0001AZ CIL_0001AZ_0002 CGP 7:78192362-78783531

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0001764 IEA neuron migration
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0002039 IEA p53 binding
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005030 IEA neurotrophin receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007623 IEP circadian rhythm
GO:0008284 IEA positive regulation of cell proliferation
GO:0010628 IEA positive regulation of gene expression
GO:0016020 IEA membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019056 IEA modulation by virus of host transcription
GO:0030335 IEA positive regulation of cell migration
GO:0032148 IEA activation of protein kinase B activity
GO:0032856 IEA activation of Ras GTPase activity
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0038179 IEA neurotrophin signaling pathway
GO:0042490 IMP mechanoreceptor differentiation
GO:0043235 ISO receptor complex
GO:0045471 IEA response to ethanol
GO:0046777 IEA protein autophosphorylation
GO:0046875 IEA ephrin receptor binding
GO:0048665 IEA neuron fate specification
GO:0048678 IEA response to axon injury
GO:0048691 IGI positive regulation of axon extension involved in regeneration
GO:0048712 IEA negative regulation of astrocyte differentiation
GO:0050927 IEA positive regulation of positive chemotaxis
GO:0051412 IEA response to corticosterone
GO:0060548 IEA negative regulation of cell death
GO:0070306 IGI lens fiber cell differentiation
GO:0071300 IEA cellular response to retinoic acid
GO:0090102 IEA cochlea development
GO:2000251 IEA positive regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000091727 ntrk3a-201 protein_coding Danio_rerio 0 859
ENST00000317501 NTRK3-002 protein_coding Homo_sapiens 0 2148
ENST00000355254 NTRK3-201 protein_coding Homo_sapiens 0 3445
ENST00000357724 NTRK3-202 protein_coding Homo_sapiens 0 2813
ENST00000360948 NTRK3-203 protein_coding Homo_sapiens 0 2907
ENST00000394480 NTRK3-001 protein_coding Homo_sapiens 0 3539
ENST00000540489 NTRK3-204 protein_coding Homo_sapiens 0 2169
ENST00000542733 NTRK3-003 protein_coding Homo_sapiens 0 2438
ENST00000557856 NTRK3-004 protein_coding Homo_sapiens 0 3446
ENST00000558306 NTRK3-017 nonsense_mediated_decay Homo_sapiens 0 244
ENST00000558576 NTRK3-007 protein_coding Homo_sapiens 0 425
ENST00000558676 NTRK3-015 protein_coding Homo_sapiens 0 2833
ENST00000559067 NTRK3-013 processed_transcript Homo_sapiens 0 405
ENST00000559188 NTRK3-005 protein_coding Homo_sapiens 0 403
ENST00000559680 NTRK3-008 processed_transcript Homo_sapiens 0 401
ENST00000559764 NTRK3-011 processed_transcript Homo_sapiens 0 606
ENST00000560017 NTRK3-010 protein_coding Homo_sapiens 0 220

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