C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: islet cell autoantigen 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000062995 Ica1 10090 - 6:8630527-8778488 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038403 Ica1-001 8630527-8778484 protein_coding
  ENSMUST00000115518 Ica1-002 8659001-8778487 protein_coding
  ENSMUST00000115519 Ica1-006 8630527-8778154 protein_coding
  ENSMUST00000115520 Ica1-004 8630527-8778439 protein_coding
  ENSMUST00000126039 Ica1-009 8749729-8770540 protein_coding
  ENSMUST00000126430 Ica1-010 8659002-8737097 protein_coding
  ENSMUST00000127398 Ica1-011 8658991-8672317 protein_coding
  ENSMUST00000135113 Ica1-003 8730440-8778488 processed_transcript
  ENSMUST00000145870 Ica1-012 8630699-8647819 processed_transcript
  ENSMUST00000151758 Ica1-008 8754634-8778123 protein_coding
  ENSMUST00000153390 Ica1-005 8658284-8778154 protein_coding
  ENSMUST00000156695 Ica1-007 8630527-8758399 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038403ENSMUST00000115519ENSMUST00000115520ENSMUST00000126039ENSMUST00000126430ENSMUST00000145870ENSMUST00000153390ENSMUST00000156695
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038403 0.865±0.31 1.133±0.34 6.475±2.45 5.305±0.53 0.172±0.00 1.392±0.39 1.143±0.16 0.739±0.39 1.112±0.80 1.096±0.41 0.437±0.23 0.309±0.10 1.075±0.55 N/A
ENSMUST00000115519 0.670±0.32 1.055±0.29 N/A N/A 0.468±0.17 N/A N/A 0.710±0.00 0.506±0.40 1.547±0.53 0.366±0.19 1.208±0.49 1.645±1.20 N/A
ENSMUST00000115520 N/A 0.865±0.22 N/A N/A 0.876±0.06 2.134±0.17 N/A N/A N/A 3.199±0.26 N/A 0.624±0.15 N/A N/A
ENSMUST00000126039 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 99.650±0.00
ENSMUST00000126430 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.776±0.00 N/A N/A
ENSMUST00000145870 N/A 2.961±0.80 N/A N/A 0.922±0.10 3.193±0.25 N/A 1.343±0.44 0.308±0.14 N/A N/A 1.195±0.36 N/A N/A
ENSMUST00000153390 0.800±0.00 N/A N/A N/A 0.825±0.12 N/A N/A N/A 0.206±0.00 N/A N/A 1.399±0.52 N/A N/A
ENSMUST00000156695 N/A 1.110±0.00 N/A N/A 0.466±0.00 N/A N/A N/A 0.205±0.14 N/A 0.252±0.05 0.340±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002EL CIL_0002EL_0002 CGP 6:8509600-8778488
CIL_0002VG CIL_0002VG_0002 CGP 6:8630527-9249032

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 ISS Golgi membrane
GO:0003674 ND molecular_function
GO:0005829 IDA cytosol
GO:0006836 IEA neurotransmitter transport
GO:0019904 IEA protein domain specific binding
GO:0030054 IEA cell junction
GO:0030667 ISS secretory granule membrane
GO:0030672 IDA synaptic vesicle membrane
GO:0046928 NAS regulation of neurotransmitter secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042608 CABZ01078431.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000003147 ICA1 islet cell autoantigen 1, 69kDa protein_coding Homo_sapiens

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