C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: islet cell autoantigen 1, 69kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000003147 ICA1 9606 - 7:8113184-8262687 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265577 ICA1-002 8113255-8262206 protein_coding
  ENST00000317367 ICA1-008 8157116-8236894 protein_coding
  ENST00000339809 ICA1-004 8113772-8262527 nonsense_mediated_decay
  ENST00000396675 ICA1-007 8113309-8262052 protein_coding
  ENST00000401396 ICA1-006 8113779-8236894 protein_coding
  ENST00000402384 ICA1-001 8113184-8262281 protein_coding
  ENST00000406470 ICA1-201 8113187-8262612 protein_coding
  ENST00000407906 ICA1-003 8156557-8262612 protein_coding
  ENST00000422063 ICA1-202 8113923-8235926 protein_coding
  ENST00000430867 ICA1-009 8218479-8262069 protein_coding
  ENST00000446305 ICA1-012 8228642-8262687 protein_coding
  ENST00000447326 ICA1-011 8218398-8262543 protein_coding
  ENST00000455539 ICA1-005 8113772-8262153 nonsense_mediated_decay
  ENST00000457755 ICA1-014 8221353-8262170 nonsense_mediated_decay
  ENST00000470696 ICA1-013 8141765-8157764 retained_intron
  ENST00000476942 ICA1-015 8218441-8218951 processed_transcript
  ENST00000486677 ICA1-010 8127873-8262145 processed_transcript
  ENST00000490041 ICA1-016 8158331-8218459 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265577ENST00000317367ENST00000339809ENST00000396675ENST00000401396ENST00000402384ENST00000406470ENST00000407906ENST00000422063ENST00000455539ENST00000470696ENST00000486677ENST00000490041
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265577 N/A 1.922±0.00 N/A 2.267±0.00 N/A N/A 1.583±0.25 N/A 0.881±0.00 N/A N/A 1.737±0.00 0.997±0.70 N/A
ENST00000317367 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.424±0.00 N/A N/A N/A
ENST00000339809 N/A N/A N/A N/A 3.542±0.00 1.770±0.00 3.286±0.00 N/A 2.597±0.00 1.780±0.57 0.073±0.00 2.752±0.23 1.952±0.00 N/A
ENST00000396675 2.660±0.00 N/A N/A 6.148±0.00 2.223±0.00 1.558±0.00 3.041±0.00 5.220±0.00 2.838±0.00 1.372±0.00 N/A 8.880±6.74 0.999±0.22 N/A
ENST00000401396 4.182±0.00 N/A N/A N/A 3.512±0.00 N/A 4.374±0.00 0.698±0.00 2.438±0.00 1.173±0.00 N/A N/A 1.422±0.00 N/A
ENST00000402384 N/A N/A N/A N/A N/A 1.896±0.00 N/A N/A N/A N/A N/A N/A 0.876±0.40 N/A
ENST00000406470 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.685±0.00 N/A N/A
ENST00000407906 N/A N/A N/A N/A 1.854±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000422063 N/A N/A N/A N/A N/A 1.077±0.00 N/A 3.607±0.00 N/A 0.940±0.00 0.761±0.00 8.021±0.00 0.736±0.00 N/A
ENST00000455539 3.387±0.00 3.403±0.00 2.044±0.00 3.978±0.00 2.606±0.48 1.536±0.79 2.194±0.53 2.971±0.00 1.005±0.53 1.311±0.00 N/A 4.944±0.00 N/A 7.287±0.00
ENST00000470696 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.279±0.00 15.344±0.00 N/A N/A
ENST00000486677 23.368±0.00 18.440±0.00 N/A N/A 27.497±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000490041 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 39.299±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002EL CIL_0002EL_0001 CGP 7:7968794-8262687
CIL_0002VG CIL_0002VG_0001 CGP 7:8113184-8752963

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 IDA Golgi membrane
GO:0003674 ND molecular_function
GO:0005737 TAS cytoplasm
GO:0005829 ISS cytosol
GO:0006836 IEA neurotransmitter transport
GO:0019904 IEA protein domain specific binding
GO:0030054 IEA cell junction
GO:0030667 IDA secretory granule membrane
GO:0030672 ISS synaptic vesicle membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042608 CABZ01078431.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000062995 Ica1 islet cell autoantigen 1 protein_coding Mus_musculus

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