C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Hedgehog-interacting protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000064325 Hhip 10090 - 8:79966115-80058006 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000079038 Hhip-001 79970345-80058006 protein_coding
  ENSMUST00000155850 Hhip-002 79966115-79990349 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000079038ENSMUST00000155850
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000079038 0.309±0.30 0.198±0.05 0.217±0.10 0.146±0.05 1.344±0.35 0.030±0.02 0.127±0.05 0.123±0.06 3.302±1.09 0.019±0.01 0.845±0.36 0.089±0.04 0.124±0.11
ENSMUST00000155850 0.116±0.04 N/A 0.776±0.00 N/A N/A 0.039±0.00 N/A 0.275±0.06 N/A 0.074±0.02 3.291±0.00 0.326±0.10 0.208±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YN CIL_0008YN_0002 VISTA 8:79537628-80138676
CIL_0007O9 CIL_0007O9_0002 UCNEbase 8:79748250-80315212
CIL_0008YM CIL_0008YM_0002 VISTA 8:79755435-80357135

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005887 IDA integral component of plasma membrane
GO:0005975 IEA carbohydrate metabolic process
GO:0007165 IDA signal transduction
GO:0007224 IMP smoothened signaling pathway
GO:0007405 IGI neuroblast proliferation
GO:0008270 ISS zinc ion binding
GO:0009887 IMP organ morphogenesis
GO:0009953 IGI dorsal/ventral pattern formation
GO:0009968 ISS negative regulation of signal transduction
GO:0009986 IDA cell surface
GO:0016525 NAS negative regulation of angiogenesis
GO:0016901 IEA oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
GO:0040036 IMP regulation of fibroblast growth factor receptor signaling pathway
GO:0045879 IDA negative regulation of smoothened signaling pathway
GO:0048038 IEA quinone binding
GO:0048705 IMP skeletal system morphogenesis
GO:0055114 IEA oxidation-reduction process
GO:0060441 IMP epithelial tube branching involved in lung morphogenesis
GO:0097108 IEA hedgehog family protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060397 hhip hedgehog interacting protein protein_coding Danio_rerio
ENSG00000164161 HHIP hedgehog interacting protein protein_coding Homo_sapiens

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