C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: v-raf-leukemia viral oncogene 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000000451 Raf1-001 ENSMUSG00000000441 10090 - 6:115618569-115676635 protein_coding

Mus musculus EnsemblGRCm38

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Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000451
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000451 51.875±8.75 44.357±2.59 33.920±4.36 42.894±23.00 45.589±5.66 46.426±4.80 46.035±9.12 35.629±2.98 33.501±3.04 45.839±1.52 42.481±2.73 52.506±11.23 34.951±10.40 16.947±0.78

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004KF CIL_0004KF_0002 CGP 6:115583544-115618670
CIL_0005SJ CIL_0005SJ_0002 CGP 6:115601938-115676635
CIL_0005SC CIL_0005SC_0002 CGP 6:115618067-115762466

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0001666 IEA response to hypoxia
GO:0004672 TAS protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005739 IEA mitochondrion
GO:0005794 ISO Golgi apparatus
GO:0005829 TAS cytosol
GO:0005886 ISS plasma membrane
GO:0007507 IEA heart development
GO:0008285 IEA negative regulation of cell proliferation
GO:0017016 IPI Ras GTPase binding
GO:0030154 IGI cell differentiation
GO:0031143 IDA pseudopodium
GO:0031333 IEA negative regulation of protein complex assembly
GO:0031434 IEA mitogen-activated protein kinase kinase binding
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0035019 IGI somatic stem cell maintenance
GO:0035556 TAS intracellular signal transduction
GO:0042802 IEA identical protein binding
GO:0043066 IEA negative regulation of apoptotic process
GO:0045104 IMP intermediate filament cytoskeleton organization
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0048011 IMP neurotrophin TRK receptor signaling pathway
GO:0071550 IMP death-inducing signaling complex assembly
GO:1902042 IGI negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000170447 MKRN2-001 protein_coding Homo_sapiens 0.0000000000002 82
ENST00000251849 RAF1-001 protein_coding Homo_sapiens 0 2758
ENST00000416093 RAF1-010 nonsense_mediated_decay Homo_sapiens 0 379
ENST00000423275 RAF1-006 nonsense_mediated_decay Homo_sapiens 0 2233
ENST00000432427 RAF1-008 protein_coding Homo_sapiens 0 1738
ENST00000442415 RAF1-007 protein_coding Homo_sapiens 0 1543
ENST00000460610 RAF1-005 retained_intron Homo_sapiens 0 442
ENST00000465826 RAF1-004 retained_intron Homo_sapiens 0 488
ENST00000471449 RAF1-009 retained_intron Homo_sapiens 0 712
ENST00000475353 RAF1-012 retained_intron Homo_sapiens 0 464
ENST00000491290 RAF1-011 retained_intron Homo_sapiens 0 529
ENST00000492690 RAF1-003 retained_intron Homo_sapiens 0 464
ENST00000494557 RAF1-002 retained_intron Homo_sapiens 0 381

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