C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Braf transforming gene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000002487 Braf-001 ENSMUSG00000002413 10090 - 6:39603237-39725463 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENSMUST00000002487
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENSMUST00000002487 4.047±0.00 7.056±2.73 3.576±0.00 2.695±0.00 3.151±0.80 3.508±0.25 3.271±0.69 4.316±0.00 1.150±0.16 4.221±0.53 2.505±1.65

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039Z CIL_00039Z_0002 CGP 6:39573873-39603382
CIL_00039Y CIL_00039Y_0002 CGP 6:39592574-39725463
CIL_000605 CIL_000605_0003 CGP 6:39603237-39810988

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0002318 IMP myeloid progenitor cell differentiation
GO:0004672 IDA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005886 IDA plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0008542 IMP visual learning
GO:0010628 IEA positive regulation of gene expression
GO:0010764 IMP negative regulation of fibroblast migration
GO:0016020 IEA membrane
GO:0030154 IGI cell differentiation
GO:0031434 IEA mitogen-activated protein kinase kinase binding
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0035019 IGI somatic stem cell maintenance
GO:0035690 IDA cellular response to drug
GO:0042127 IGI regulation of cell proliferation
GO:0042802 IEA identical protein binding
GO:0043005 IDA neuron projection
GO:0043066 IEA negative regulation of apoptotic process
GO:0043367 IMP CD4-positive, alpha-beta T cell differentiation
GO:0043368 IMP positive T cell selection
GO:0043434 IEA response to peptide hormone
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0044297 IDA cell body
GO:0046632 IMP alpha-beta T cell differentiation
GO:0046982 IEA protein heterodimerization activity
GO:0051291 IEA protein heterooligomerization
GO:0051496 IGI positive regulation of stress fiber assembly
GO:0051591 IEA response to cAMP
GO:0060291 IMP long-term synaptic potentiation
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0071277 IEA cellular response to calcium ion
GO:1900026 IMP positive regulation of substrate adhesion-dependent cell spreading
GO:2000301 IMP negative regulation of synaptic vesicle exocytosis
GO:2000352 IMP negative regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000288602 BRAF-001 protein_coding Homo_sapiens 0 1664
ENST00000445336 BRAFP1-001 unprocessed_pseudogene Homo_sapiens 0 1426
ENST00000469930 BRAF-004 retained_intron Homo_sapiens 0 372
ENST00000476279 NDUFB2-003 protein_coding Homo_sapiens 0 678
ENST00000479537 BRAF-005 nonsense_mediated_decay Homo_sapiens 0 494
ENST00000496384 BRAF-003 protein_coding Homo_sapiens 0 3059
ENST00000497784 BRAF-002 nonsense_mediated_decay Homo_sapiens 0 1664

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