C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast growth factor receptor 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000393637 FGFR4-002 ENSG00000160867 9606 + 5:177089567-177097769 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartENST00000393637
Transcript ID Breast Heart
ENST00000393637 0.058±0.00 0.018±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000OR CIL_0000OR_0002 CGP 5:177022696-177098144
CIL_0000OQ CIL_0000OQ_0002 CGP 5:177086886-177300215

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0005007 IGI:IEA fibroblast growth factor-activated receptor activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005576 IEA extracellular region
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005783 IDA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0005911 IDA cell-cell junction
GO:0006468 IEA protein phosphorylation
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008201 IDA heparin binding
GO:0008284 IDA:IEA positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 IPI:IEA fibroblast growth factor receptor signaling pathway
GO:0010715 IMP regulation of extracellular matrix disassembly
GO:0016021 IEA integral component of membrane
GO:0016477 IMP cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017134 IPI fibroblast growth factor binding
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019216 ISS regulation of lipid metabolic process
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042593 ISS glucose homeostasis
GO:0045087 TAS innate immune response
GO:0045862 IMP positive regulation of proteolysis
GO:0046777 IDA protein autophosphorylation
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0048554 IMP positive regulation of metalloenzyme activity
GO:0055062 ISS phosphate ion homeostasis
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0070857 IMP regulation of bile acid biosynthetic process
GO:2000188 ISS regulation of cholesterol homeostasis
GO:2000573 IMP positive regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000005452 Fgfr4-001 protein_coding Mus_musculus 0 1319
ENSMUST00000162167 Fgfr4-003 retained_intron Mus_musculus 0 483
ENSMUST00000117073 Fgfr2-020 protein_coding Mus_musculus 7e-33 147
ENSMUST00000121080 Fgfr2-019 protein_coding Mus_musculus 7e-33 147
ENSMUST00000118296 Fgfr2-018 protein_coding Mus_musculus 7e-33 147
ENSMUST00000122448 Fgfr2-017 protein_coding Mus_musculus 7e-33 147
ENSMUST00000117357 Fgfr2-016 protein_coding Mus_musculus 7e-33 147
ENSMUST00000120141 Fgfr2-015 protein_coding Mus_musculus 7e-33 147
ENSMUST00000117858 Fgfr2-014 protein_coding Mus_musculus 7e-33 147
ENSMUST00000117691 Fgfr2-013 protein_coding Mus_musculus 7e-33 147
ENSMUST00000117089 Fgfr2-012 protein_coding Mus_musculus 7e-33 147
ENSMUST00000119260 Fgfr2-011 protein_coding Mus_musculus 7e-33 147
ENSMUST00000120187 Fgfr2-003 protein_coding Mus_musculus 7e-33 147
ENSMUST00000122054 Fgfr2-004 protein_coding Mus_musculus 7e-33 147
ENSMUST00000117872 Fgfr2-002 protein_coding Mus_musculus 7e-33 147
ENSMUST00000153166 Fgfr2-001 nonsense_mediated_decay Mus_musculus 7e-33 147
ENSMUST00000127091 Fgfr2-021 nonsense_mediated_decay Mus_musculus 3e-22 111
ENSMUST00000117754 Fgfr2-009 protein_coding Mus_musculus 0.000000000000001 90
ENSMUST00000121064 Fgfr2-008 protein_coding Mus_musculus 0.000000000000001 90

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