C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast growth factor receptor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000412135 FGFR3-202 ENSG00000068078 9606 + 4:1793312-1808872 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyENST00000412135
Transcript ID Kidney
ENST00000412135 0.476±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TX CIL_0007TX_0001 VISTA 4:1311752-1912379
CIL_0006V2 CIL_0006V2_0001 CGP 4:1721490-1808872
CIL_0006V3 CIL_0006V3_0001 CGP 4:1793307-1856247

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 TAS skeletal system development
GO:0001958 TAS endochondral ossification
GO:0002062 TAS chondrocyte differentiation
GO:0003416 TAS endochondral bone growth
GO:0004672 IEA protein kinase activity
GO:0004713 IDA:IEA protein tyrosine kinase activity
GO:0005007 IMP:IEA fibroblast growth factor-activated receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005576 IEA extracellular region
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0005925 TAS focal adhesion
GO:0006468 IEA protein phosphorylation
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007259 TAS JAK-STAT cascade
GO:0008284 IMP:IEA positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 IDA:IEA fibroblast growth factor receptor signaling pathway
GO:0010518 IMP positive regulation of phospholipase activity
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017134 IPI fibroblast growth factor binding
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0030282 ISS bone mineralization
GO:0031410 IEA cytoplasmic vesicle
GO:0035988 TAS chondrocyte proliferation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042511 IMP positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517 IMP positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0043410 IMP positive regulation of MAPK cascade
GO:0043552 IMP positive regulation of phosphatidylinositol 3-kinase activity
GO:0045087 TAS innate immune response
GO:0046777 IDA protein autophosphorylation
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0048640 ISS negative regulation of developmental growth
GO:0060349 TAS bone morphogenesis
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0070977 ISS bone maturation
GO:1902178 IMP fibroblast growth factor receptor apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000169212 Fgfr3-202 protein_coding Mus_musculus 0 931
ENSMUST00000171509 Fgfr3-203 protein_coding Mus_musculus 0 911
ENSMUST00000114411 Fgfr3-201 protein_coding Mus_musculus 0 911
ENSMUST00000164207 Fgfr3-008 protein_coding Mus_musculus 0 911
ENSMUST00000067150 Fgfr3-001 protein_coding Mus_musculus 0 911
ENSMUST00000134610 Fgfr3-003 retained_intron Mus_musculus 0 822
ENSMUST00000087820 Fgfr3-002 protein_coding Mus_musculus 0 588
ENSMUST00000181298 Fgfr3-009 processed_transcript Mus_musculus 0 531
ENSMUST00000005452 Fgfr4-001 protein_coding Mus_musculus 0 276
ENSMUST00000132724 Fgfr3-006 retained_intron Mus_musculus 0 250

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