C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor coactivator 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000006037 Ncoa2-002 ENSMUSG00000005886 10090 - 1:13142475-13374083 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000006037
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000006037 5.137±2.51 4.508±1.66 3.199±0.00 5.516±3.27 5.243±2.08 4.941±0.73 2.632±0.83 4.846±1.45 2.087±0.54 3.843±0.84 7.025±2.75 4.768±3.87 10.881±5.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ME CIL_0007ME_0002 UCNEbase 1:13097855-13197231
CIL_0003BO CIL_0003BO_0002 CGP 1:13113457-13374083
CIL_0003BN CIL_0003BN_0002 CGP 1:13139105-13589910

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003682 IDA chromatin binding
GO:0003713 IDA transcription coactivator activity
GO:0004402 IEA histone acetyltransferase activity
GO:0004871 IEA signal transducer activity
GO:0005102 IDA receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0008134 IPI transcription factor binding
GO:0010906 IMP regulation of glucose metabolic process
GO:0016573 IEA histone acetylation
GO:0016922 IEA ligand-dependent nuclear receptor binding
GO:0030374 IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030375 IDA thyroid hormone receptor coactivator activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:2000273 IDA positive regulation of receptor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000452400 NCOA2-001 protein_coding Homo_sapiens 0 5969
ENST00000518287 NCOA2-002 nonsense_mediated_decay Homo_sapiens 0 3518
ENST00000518363 NCOA2-005 protein_coding Homo_sapiens 0 1941
ENST00000519724 NCOA2-004 protein_coding Homo_sapiens 3e-25 119
ENST00000520416 NCOA2-003 protein_coding Homo_sapiens 1e-24 117
ENST00000521239 NCOA2-007 retained_intron Homo_sapiens 0 405
ENST00000524223 NCOA2-008 processed_transcript Homo_sapiens 0 905

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